Evidence map›Paper›PMID 34997853›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2022

Cortical thickness across the cingulate gyrus in schizophrenia and its association to illness duration and memory performance.

J-W Thielen, B W Müller, D-I Chang, A Krug, S Mehl, A Rapp, H Walter, G Winterer, K Vogeley, S Klingberg and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

J-W ThielenDepartment of Psychiatry and Psychotherapy, LVR-Hospital Essen, Faculty of Medicine, University of Duisburg-Essen, Duisburg, Germany. jan-willem.thielen@uni-due.de.
B W MüllerDepartment of Psychiatry and Psychotherapy, LVR-Hospital Essen, Faculty of Medicine, University of Duisburg-Essen, Duisburg, Germany.
D-I ChangDepartment of Psychiatry, LWL University Hospital Bochum, Ruhr University Bochum, Bochum, Germany.
A KrugDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
S MehlDepartment of Psychiatry and Psychotherapy and Center for Mind, Brain and Behavior (MCMBB), Philipps-University, Marburg, Germany.
A RappDepartment of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.
H WalterDivision of Mind and Brain Research, Department of Psychiatry and Psychotherapy CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, and Berlin Institute of Health, Berlin, Germany.
G WintererDepartment of Psychiatry and Psychotherapy, University of Berlin, Berlin, Germany.
K VogeleyDepartment of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
S KlingbergDepartment of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.
M WagnerDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
T KircherDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
University of Bonn · DEUniversity of Tübingen · DEForschungszentrum Jülich · DEFreie Universität Berlin · DELWL-Universitätsklinikum Bochum · DEPhilipps University of Marburg · DEUniversity of Duisburg-Essen · DEUniversity of Wuppertal · DE

Funding

Bundesministerium für Bildung und Forschung 01GV0618
6 · The paper itself

Abstract

Schizophrenia has been associated with structural brain abnormalities and cognitive deficits that partly change during the course of illness. In the present study, cortical thickness in five subregions of the cingulate gyrus was assessed in 44 patients with schizophrenia-spectrum disorder and 47 control persons and related to illness duration and memory capacities. In the patients group, cortical thickness was increased in the posterior part of the cingulate gyrus and related to illness duration whereas cortical thickness was decreased in anterior parts unrelated to illness duration. In contrast, cortical thickness was related to episodic and working memory performance only in the anterior but not posterior parts of the cingulate gyrus. Our finding of a posterior cingulate increase may point to either increased parietal communication that is accompanied by augmented neural plasticity or to effects of altered neurodegenerative processes in schizophrenia.

Indexed as

Gyrus CinguliSchizophreniaCognitionHumansMagnetic Resonance ImagingMemory, Short-TermCingulate gyrusMagnetic resonance imagingNeuropsychological assessmentSchizophrenia

Identifiers

PMID34997853
PMCPMC9508009
OpenAlexW4206260396

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.