Evidence map›Paper›PMID 34997555›Full record

ArticleCardiovascular engineering and technology2022

Deep Learning to Automatically Segment and Analyze Abdominal Aortic Aneurysm from Computed Tomography Angiography.

Francesca Brutti, Alice Fantazzini, Alice Finotello, Lucas Omar Müller, Ferdinando Auricchio, Bianca Pane, Giovanni Spinella, Michele Conti

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In one paragraph

Article in Cardiovascular engineering and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

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  15. A Statistical Shape Model of Infrarenal Aortic Necks in Patients With and Without Late Type Ia Endoleak After Endovascular Aneurysm Repair.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Francesca Brutti *Department of Mathematics, University of Trento, Trento, Italy.
Alice Fantazzini *Department of Experimental Medicine, University of Genoa, Genoa, Italy.
Alice FinotelloDepartment of Integrated Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy.
Lucas Omar MüllerDepartment of Mathematics, University of Trento, Trento, Italy.
Ferdinando AuricchioDepartment of Civil Engineering and Architecture, University of Pavia, Via Ferrata 3, 27100, Pavia, Italy.
Bianca PaneVascular and Endovascular Surgery Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Giovanni SpinellaVascular and Endovascular Surgery Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Michele ContiDepartment of Civil Engineering and Architecture, University of Pavia, Via Ferrata 3, 27100, Pavia, Italy. michele.conti@unipv.it.ORCID 0000-0003-1275-0653
Ospedale Policlinico San Martino · ITUniversity of Pavia · ITUniversity of Trento · ITCamelot Biomedical Systems (Italy) · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough segmentation of Abdominal Aortic Aneurysms (AAA) thrombus is a crucial step for both the planning of endovascular treatment and the monitoring of the intervention's outcome, it is still performed manually implying time consuming operations as well as operator dependency. The present paper proposes a fully automatic pipeline to segment the intraluminal thrombus in AAA from contrast-enhanced Computed Tomography Angiography (CTA) images and to subsequently analyze AAA geometry.

methodsA deep-learning-based pipeline is developed to localize and segment the thrombus from the CTA scans. The thrombus is first identified in the whole sub-sampled CTA, then multi-view U-Nets are combined together to segment the thrombus from the identified region of interest. Polygonal models are generated for the thrombus and the lumen. The lumen centerline is automatically extracted from the lumen mesh and used to compute the aneurysm and lumen diameters.

resultsThe proposed multi-view integration approach returns an improvement in thrombus segmentation with respect to the single-view prediction. The thrombus segmentation model is trained over a training set of 63 CTA and a validation set of 8 CTA scans. By comparing the thrombus segmentation predicted by the model with the ground truth data, a Dice Similarity Coefficient (DSC) of 0.89 ± 0.04 is achieved. The AAA geometry analysis provided an Intraclass Correlation Coefficient (ICC) of 0.92 and a mean-absolute difference of 3.2 ± 2.4 mm, for the measurements of the total diameter of the aneurysm. Validation of both thrombus segmentation and aneurysm geometry analysis is performed over a test set of 14 CTA scans.

conclusionThe developed deep learning models can effectively segment the thrombus from patients affected by AAA. Moreover, the diameters automatically extracted from the AAA show high correlation with those manually measured by experts.

Indexed as

Aortic Aneurysm, AbdominalDeep LearningThrombosisComputed Tomography AngiographyHumansAbdominal Aortic AneurysmConvolutional Neural NetworkMulti-view integrationThrombus segmentation

Identifiers

PMID34997555
OpenAlexW4205826745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.