Evidence map›Paper›PMID 34997255›Full record

ArticleArchives of toxicology2022

Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues.

Hansruedi Glatt, Wolfram Engst, Simone Florian, Monika Schreiner, Chimgee Baasanjav-Gerber

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Genotoxicity Studies of Indole-3-carbinol andPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hansruedi GlattGerman Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, 14558, Nuthetal, Germany. glatt@dife.de.ORCID 0000-0001-6053-0562
Wolfram EngstGerman Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, 14558, Nuthetal, Germany.
Simone FlorianGerman Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, 14558, Nuthetal, Germany.
Monika SchreinerLeibniz Institute of Vegetable and Ornamental Crops (IGZ), 14979, Grossbeeren, Germany.
Chimgee Baasanjav-GerberGerman Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, 14558, Nuthetal, Germany.
German Institute of Human Nutrition · DEFederal Institute for Risk Assessment · DELeibniz Institute of Vegetable and Ornamental Crops · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juices of Brassica vegetables are mutagenic and form characteristic DNA adducts in bacteria and mammalian cells. In this study, we examined whether such adducts are also formed in vivo in animal models. Rats fed raw broccoli ad libitum in addition to normal laboratory chow for 5 weeks showed one major adduct spot and sometimes an additional minor adduct spot in liver, kidney, lung, blood and the gastrointestinal tract, as determined by

Indexed as

AnimalsBrassicaChromatography, LiquidDNA AdductsGlucosinolatesIndolesMaleRatsRats, Sprague-DawleyTandem Mass SpectrometryVegetables1-methoxy-3-indolylmethyl glucosinolateDNA AdductsGlucosinolatesIndolesneoglucobrassicinBroccoliDNA adductsGlucosinolatesNeoglucobrassicin

Identifiers

PMID34997255
PMCPMC8850215
OpenAlexW4205579172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.