Evidence map›Paper›PMID 34997177›Full record

ArticleScientific reports2022

Ethanol reduces the minimum alveolar concentration of sevoflurane in rats.

Johannes Müller, Walter Plöchl, Paul Mühlbacher, Alexandra Graf, Anne-Margarethe Kramer, Bruno Karl Podesser, Thomas Stimpfl, Thomas Hamp

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Johannes MüllerDepartment of Anaesthesia, Intensive Care and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria. johannes.mueller@meduniwien.ac.at.
Walter PlöchlDepartment of Anaesthesia, Intensive Care and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria.
Paul MühlbacherDepartment of Anaesthesia, Intensive Care and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria.
Alexandra GrafInstitute for Medical Statistics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Anne-Margarethe KramerCenter for Biomedical Research, Medical University of Vienna, Vienna, Austria.
Bruno Karl PodesserCenter for Biomedical Research, Medical University of Vienna, Vienna, Austria.
Thomas StimpflDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Thomas HampDepartment of Anaesthesia, Intensive Care and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATStatistics Austria · AT

Funding

Chiesi Pharmaceuticals GmbH, Vienna, Austria UE73801027
6 · The paper itself

Abstract

A high number of trauma patients are under the influence of alcohol. Since many of them need immediate surgical procedures, it is imperative to be aware of the interaction of alcohol with general anesthesia. To counter challenges that arise from clinical studies, we designed an animal experiment in which 48 adult Wistar rats either received 1 g · kg

Indexed as

Administration, InhalationAnesthetics, InhalationAnimalsBlood Alcohol ContentDose-Response Relationship, DrugDrug InteractionsEthanolFemaleInjections, IntraperitonealMalePulmonary AlveoliRatsRats, WistarSevofluraneTissue DistributionAnesthetics, InhalationBlood Alcohol ContentEthanolSevoflurane

Identifiers

PMID34997177
PMCPMC8741959
OpenAlexW4205568641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.