Evidence map›Paper›PMID 34997124›Full record

ArticleScientific reports2022

Colonoscopic image synthesis with generative adversarial network for enhanced detection of sessile serrated lesions using convolutional neural network.

Dan Yoon, Hyoun-Joong Kong, Byeong Soo Kim, Woo Sang Cho, Jung Chan Lee, Minwoo Cho, Min Hyuk Lim, Sun Young Yang, Seon Hee Lim, Jooyoung Lee and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Dan Yoon *Interdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul, 08826, South Korea.
Hyoun-Joong Kong *Transdisciplinary Department of Medicine and Advanced Technology, Seoul National University Hospital, Seoul, 03080, South Korea.
Byeong Soo KimInterdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul, 08826, South Korea.
Woo Sang ChoInterdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul, 08826, South Korea.
Jung Chan LeeDepartment of Biomedical Engineering, Seoul National University College of Medicine, Seoul, 03080, South Korea.
Minwoo ChoTransdisciplinary Department of Medicine and Advanced Technology, Seoul National University Hospital, Seoul, 03080, South Korea.
Min Hyuk LimDepartment of Biomedical Engineering, Seoul National University College of Medicine, Seoul, 03080, South Korea.
Sun Young YangDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Seon Hee LimDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Jooyoung LeeDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Ji Hyun SongDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Goh Eun ChungDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Ji Min ChoiDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Hae Yeon KangDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea.
Jung Ho BaeDepartment of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 06236, South Korea. newsanapd@naver.com.
Sungwan KimDepartment of Biomedical Engineering, Seoul National University College of Medicine, Seoul, 03080, South Korea. sungwan@snu.ac.kr.
Seoul National University Hospital · KRSeoul National University · KR

Funding

Ministry of Science and ICT, South Korea IITP-2021-2018-0-01833
6 · The paper itself

Abstract

Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. To be an effective system, it is important to detect additional polyps that may be easily missed by endoscopists. Sessile serrated lesions (SSLs) are a precursor to colorectal cancer with a relatively higher miss rate, owing to their flat and subtle morphology. Colonoscopy CADe systems could help endoscopists; however, the current systems exhibit a very low performance for detecting SSLs. We propose a polyp detection system that reflects the morphological characteristics of SSLs to detect unrecognized or easily missed polyps. To develop a well-trained system with imbalanced polyp data, a generative adversarial network (GAN) was used to synthesize high-resolution whole endoscopic images, including SSL. Quantitative and qualitative evaluations on GAN-synthesized images ensure that synthetic images are realistic and include SSL endoscopic features. Moreover, traditional augmentation methods were used to compare the efficacy of the GAN augmentation method. The CADe system augmented with GAN synthesized images showed a 17.5% improvement in sensitivity on SSLs. Consequently, we verified the potential of the GAN to synthesize high-resolution images with endoscopic features and the proposed system was found to be effective in detecting easily missed polyps during a colonoscopy.

Indexed as

ColonoscopyEarly Detection of CancerImage Interpretation, Computer-AssistedNeural Networks, ComputerColonic PolypsColorectal NeoplasmsDatabases, FactualHumansPredictive Value of TestsProspective StudiesReproducibility of ResultsRetrospective Studies

Identifiers

PMID34997124
PMCPMC8741803
OpenAlexW4205566005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.