Evidence map›Paper›PMID 34997107›Full record

ArticleScientific reports2022

Identification and validation of plasma biomarkers for diagnosis of breast cancer in South Asian women.

Thangarajan Rajkumar, Sathyanarayanan Amritha, Veluswami Sridevi, Gopisetty Gopal, Kesavan Sabitha, Sundersingh Shirley, Rajaraman Swaminathan

Abstract readComparative StudyValidation Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  3. Review
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  6. Article
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  8. Article
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  10. Article
  11. Article
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  14. Omics-Based Investigations of Breast Cancer.Molecules (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thangarajan RajkumarDepartment of Molecular Oncology, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India. drtrajkumar@gmail.com.
Sathyanarayanan AmrithaDepartment of Molecular Oncology, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India.
Veluswami SrideviDepartment of Surgical Oncology, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India.
Gopisetty GopalDepartment of Molecular Oncology, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India.
Kesavan SabithaDepartment of Molecular Oncology, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India.
Sundersingh ShirleyDepartment of Pathology, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India.
Rajaraman SwaminathanDepartment of Epidemiology and Biostatistics, Cancer Institute (WIA), 38, Sardar Patel Road, Chennai, 600036, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common malignancy among women globally. Development of a reliable plasma biomarker panel might serve as a non-invasive and cost-effective means for population-based screening of the disease. Transcriptomic profiling of breast tumour, paired normal and apparently normal tissues, followed by validation of the shortlisted genes using TaqMan

Indexed as

Gene Expression ProfilingAdaptor Proteins, Signal TransducingAdultAsian PeopleBiomarkers, TumorBreast NeoplasmsCase-Control StudiesDNA MethylationEpigenesis, GeneticFemaleHumansIndiaMCF-7 CellsMiddle AgedOligonucleotide Array Sequence AnalysisPredictive Value of TestsAdaptor Proteins, Signal TransducingBiomarkers, TumorDACT2 protein, humanSOSTDC1 protein, humanWIF1 protein, human

Identifiers

PMID34997107
PMCPMC8742108

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.