Observational studyScientific reports2022
Mechanical power normalized to lung-thorax compliance indicates weaning readiness in prolonged ventilated patients.
Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Trial
- Mechanical Power as a Predictor of Outcomes During Mechanical Ventilation in Coronavirus Disease 2019 (COVID-19): An Updated Systematic Review.Journal of clinical medicine · 2026Review
- Tracheostomy timing and weaning outcomes following prolonged mechanical ventilation.BMC pulmonary medicine · 2026Observational
- Mechanical power normalisation methods to predict ICU mortality: a retrospective cohort study.Annals of intensive care · 2025Article
- The association of ventilator mechanical power with weaning outcomes in intensive care unit patients: a narrative review.Journal of thoracic disease · 2025Review
- Article
- Mechanical Power Ratio and Respiratory Treatment Escalation in COVID-19 Pneumonia: A Secondary Analysis of a Prospectively Enrolled Cohort.Anesthesiology · 2023Article
- Mechanical Power Density Predicts Prolonged Ventilation Following Double Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Mechanical power is associated with weaning outcome in critically ill mechanically ventilated patients.Scientific reports · 2022Article
- Ventilatory ratio and mechanical power in prolonged mechanically ventilated COVID-19 patientsTherapeutic advances in respiratory diseaseObservational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since critical respiratory muscle workload is a significant determinant of weaning failure, applied mechanical power (MP) during artificial ventilation may serve for readiness testing before proceeding on a spontaneous breathing trial (SBT). Secondary analysis of a prospective, observational study in 130 prolonged ventilated, tracheotomized patients. Calculated MP's predictive SBT outcome performance was determined using the area under receiver operating characteristic curve (AUROC), measures derived from k-fold cross-validation (likelihood ratios, Matthew's correlation coefficient [MCC]), and a multivariable binary logistic regression model. Thirty (23.1%) patients failed the SBT, with absolute MP presenting poor discriminatory ability (MCC 0.26; AUROC 0.68, 95%CI [0.59‒0.75], p = 0.002), considerably improved when normalized to lung-thorax compliance (LTC
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