Evidence map›Paper›PMID 34997001›Full record

ArticleScientific reports2022

Geographic and temporal variation in racial and ethnic disparities in SARS-CoV-2 positivity between February 2020 and August 2021 in the United States.

Jacqueline M Ferguson, Amy C Justice, Thomas F Osborne, Hoda S Abdel Magid, Amanda L Purnell, Christopher T Rentsch

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Nationwide population-based infection- and vaccine-induced SARS-CoV-2 antibody seroprevalence in Germany in autumn/winter 2021/2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jacqueline M FergusonCenter for Innovation to Implementation, VA Palo Alto Healthcare System, US Department of Veterans Affairs, MDP-152, 795 Willow Rd, Menlo Park, CA, 94025, USA. jacqueline.ferguson@va.gov.
Amy C JusticeVA Connecticut Healthcare System, US Department of Veterans Affairs, West Haven, CT, USA.
Thomas F OsborneCenter for Innovation to Implementation, VA Palo Alto Healthcare System, US Department of Veterans Affairs, MDP-152, 795 Willow Rd, Menlo Park, CA, 94025, USA.
Hoda S Abdel MagidCenter for Innovation to Implementation, VA Palo Alto Healthcare System, US Department of Veterans Affairs, MDP-152, 795 Willow Rd, Menlo Park, CA, 94025, USA.
Amanda L PurnellVA Central Office, US Department of Veterans Affairs, Washington, DC, USA.
Christopher T RentschVA Connecticut Healthcare System, US Department of Veterans Affairs, West Haven, CT, USA.
United States Department of Veterans Affairs · USCenter for Innovation · USStanford University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
3/3 COMpAAAS Tripartite: ART-CC, KP, and VAU01AA026224 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2017 to 2021
$2.9M
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01-AA020790NIAAA NIH HHS U01 AA026224NIAAA NIH HHS U01-AA026224NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U10-AA013566NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24-AA020794
6 · The paper itself

Abstract

The coronavirus pandemic has disproportionally impacted racial and ethnic minority communities in the United States. Patterns of these disparities may be changing over time as outbreaks occur in different communities. Utilizing electronic health record data from the US Department of Veterans Affairs (VA), we estimated odds ratios, stratified by time period and region, for testing positive among 1,313,402 individuals tested for SARS-CoV-2 between February 12, 2020 and August 16, 2021 at VA medical facilities. We adjusted for personal characteristics (sex, age, rural/urban residence, VA facility) and a wide range of clinical characteristics that have been evaluated in prior SARS-CoV-2 reports and could potentially explain racial/ethnic disparities in SARS-CoV-2. Our study found racial and ethnic disparities for testing positive were most pronounced at the beginning of the pandemic and decreased over time. A key finding was that the disparity among Hispanic individuals attenuated but remained elevated, while disparities among Asian individuals reversed by March 1, 2021. The variation in racial and ethnic disparities in SARS-CoV-2 positivity by time and region, independent of underlying health status and other demographic characteristics in a nationwide cohort, provides important insight for strategies to prevent further outbreaks.

Indexed as

AdultAgedAged, 80 and overCOVID-19Ethnic and Racial MinoritiesFemaleHispanic or LatinoHumansMaleMiddle AgedRacial GroupsRisk FactorsRural PopulationSARS-CoV-2United StatesUrban Population

Identifiers

PMID34997001
PMCPMC8741774
OpenAlexW4206347739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.