Evidence map›Paper›PMID 34996990›Full record

Observational studyScientific reports2022

Artificial intelligence predicts clinically relevant atrial high-rate episodes in patients with cardiac implantable electronic devices.

Min Kim, Younghyun Kang, Seng Chan You, Hyung-Deuk Park, Sang-Soo Lee, Tae-Hoon Kim, Hee Tae Yu, Eue-Keun Choi, Hyoung-Seob Park, Junbeom Park and 7 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Artificial intelligence-powered advancements in atrial fibrillation diagnostics: a systematic review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Min Kim *Division of Cardiology, Chungbuk National University Hospital, Cheongju, Korea.
Younghyun Kang *Medtronic Korea, Seoul, Korea.
Seng Chan YouDepartment of Preventive Medicine and Public Health, Yonsei University College of Medicine, Seoul, Korea.
Hyung-Deuk ParkMedtronic Korea, Seoul, Korea.
Sang-Soo LeeMedtronic Korea, Seoul, Korea.
Tae-Hoon KimDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Hee Tae YuDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Eue-Keun ChoiDepartment of Cardiology, Seoul National University Hospital, Seoul, Korea.
Hyoung-Seob ParkDivision of Cardiology, Keimyung University Hospital, Daegu, Korea.
Junbeom ParkDepartment of Cardiology, Ewha Womans University Hospital, Seoul, Korea.
Young Soo LeeDivision of Cardiology, Daegu Catholic University Hospital, Daegu, Korea.
Ki-Woon KangDivision of Cardiology, Eulji University Hospital, Daejeon, Korea.
Jaemin ShimDepartment of Cardiology, Korea University Hospital, Seoul, Korea.
Jung-Hoon SungDepartment of Cardiology, CHA Bundang University Hospital, Seongnam, Korea.
Il-Young OhDepartment of Cardiology, Seoul National University Bundang Hospital, Seongnam, Korea.
Jong Sung ParkDivision of Cardiology, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan, 49201, Republic of Korea. thinkmed@dae.ac.krm.
Boyoung JoungDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. cby6908@yuhs.ac.

Funding

Ministry of Health and Welfare HI15C1200
6 · The paper itself

Abstract

To assess the utility of machine learning (ML) algorithms in predicting clinically relevant atrial high-rate episodes (AHREs), which can be recorded by a pacemaker. We aimed to develop ML-based models to predict clinically relevant AHREs based on the clinical parameters of patients with implanted pacemakers in comparison to logistic regression (LR). We included 721 patients without known atrial fibrillation or atrial flutter from a prospective multicenter (11 tertiary hospitals) registry comprising all geographical regions of Korea from September 2017 to July 2020. Predictive models of clinically relevant AHREs were developed using the random forest (RF) algorithm, support vector machine (SVM) algorithm, and extreme gradient boosting (XGB) algorithm. Model prediction training was conducted by seven hospitals, and model performance was evaluated using data from four hospitals. During a median follow-up of 18 months, clinically relevant AHREs were noted in 104 patients (14.4%). The three ML-based models improved the discrimination of the AHREs (area under the receiver operating characteristic curve: RF: 0.742, SVM: 0.675, and XGB: 0.745 vs. LR: 0.669). The XGB model had a greater resolution in the Brier score (RF: 0.008, SVM: 0.008, and XGB: 0.021 vs. LR: 0.013) than the other models. The use of the ML-based models in patient classification was associated with improved prediction of clinically relevant AHREs after pacemaker implantation.

Indexed as

Artificial IntelligenceAtrial FibrillationAgedAged, 80 and overClinical Decision RulesCohort StudiesFemaleHumansMachine LearningMaleModels, StatisticalPacemaker, ArtificialProspective StudiesRegistriesRepublic of KoreaROC Curve

Identifiers

PMID34996990
PMCPMC8741914

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.