Evidence map›Paper›PMID 34996492›Full record

ArticleParticle and fibre toxicology2022

Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM

Ulrike Luderer, Jinhwan Lim, Laura Ortiz, Johnny D Nguyen, Joyce H Shin, Barrett D Allen, Lisa S Liao, Kelli Malott, Veronique Perraud, Lisa M Wingen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Ambient PMEnvironmental epidemiology (Philadelphia, Pa.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Timing determines programming of energy homeostasis by maternal PMEnvironmental pollution (Barking, Essex : 1987) · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Ulrike LudererDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA. uluderer@uci.edu.ORCID 0000-0002-8639-1326
Jinhwan LimDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
Laura OrtizDepartment of Medicine, University of California Irvine, Irvine, CA, 92617, USA.
Johnny D NguyenDepartment of Medicine, University of California Irvine, Irvine, CA, 92617, USA.
Joyce H ShinDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
Barrett D AllenDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
Lisa S LiaoDepartment of Medicine, University of California Irvine, Irvine, CA, 92617, USA.
Kelli MalottDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
Veronique PerraudDepartment of Chemistry, University of California Irvine, Irvine, CA, 92617, USA.
Lisa M WingenDepartment of Chemistry, University of California Irvine, Irvine, CA, 92617, USA.
Rebecca J ArechavalaDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
Bishop BlissDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
David A HermanDepartment of Medicine, University of California Irvine, Irvine, CA, 92617, USA.
Michael T KleinmanDepartment of Environmental and Occupational Health, University of California Irvine, 100 Theory Drive, Suite 100, Irvine, CA, 92617, USA.
University of California, Irvine · US

Funding

Developmental Gene-Environment Interactions and Premature Ovarian FailureR01ES020454 · NIEHS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LUDERER, ULRIKE · 2012 to 2021
$4.7M
NIEHS NIH HHS R01 ES020454
6 · The paper itself

Abstract

backgroundFine particulate matter (PM

resultsHyperlipidemic apolipoprotein E (Apoe) null ovary-intact or ovariectomized female mice and testis-intact male mice were exposed to concentrated ambient PM

conclusionsThese results demonstrate that subchronic PM

Indexed as

Ovarian ReserveAnimalsApolipoproteinsApolipoproteins EFemaleMaleMiceMice, KnockoutOvarian FollicleParticulate MatterApolipoproteinsApolipoproteins EParticulate MatterAtherosclerosisBlood pressureHeart rate variabilityOvarian follicleOvariectomyOvaryPM2.5Sex difference

Identifiers

PMID34996492
PMCPMC8740366
OpenAlexW4206773992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.