Evidence map›Paper›PMID 34996489›Full record

ArticleDiagnostic pathology2022

NUT midline carcinoma as a primary lung tumor treated with anlotinib combined with palliative radiotherapy: a case report.

Jin Jiang, Yikun Ren, Chengping Xu, Xing Lin

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostic pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Jin JiangDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Yikun RenDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Chengping XuDepartment of Pathology, The Southwest Hospital, the Southwest Hospital of Army Medical University, Chongqing, 400038, China.
Xing LinDepartment of Biological Immunotherapy, Chongqing University Cancer Hospital, Chongqing Cancer Institute, Chongqing Cancer Hospital, Shapingba District, Chongqing, 400030, China. lx15002345792@126.com.
Army Medical University · CNChongqing Cancer Hospital · CNChongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

The Chinese Medicine Science and Technology project of Chongqing Municipal Health committee 2021ZY3794The Natural Science Foundation of Chongqing cstc2019jcyj-msxmX0630The Natural Science Foundation of Chongqing cstc2020jcyj-msxmX0325
6 · The paper itself

Abstract

backgroundNUT (nuclear protein in testis) midline carcinoma (NMC) is a rapidly progressive tumor arising from midline structures. Recent cases have reported that the poor prognosis with a median survival of 6.7 months and a 2 years overall survival of 19% due to limited treatment. Based on the effect of arotinib on inhibiting tumor growth and angiogenesis. We present one patient case treated with anlotinib and radiotherapy. CASE PRESENTATION: Here, we describe a 33-year old patient who complained of cough and chest pain and was diagnosed as a pulmonary NMC through CT scan, FISH and immunohistochemistry. In addition, we initially demonstrated that anlotinib combined with palliative radiotherapy could significantly prevent the tumor growth in a pulmonary NMC.

conclusionThe report indicated that anlotinib combined with palliative radiotherapy could inhibit the tumor progression in a pulmonary NMC, which may provide a combined therapy to pulmonary NMC in the future.

Indexed as

Palliative CareAdultAntineoplastic AgentsCarcinomaFatal OutcomeHumansIndolesLung NeoplasmsMaleQuinolinesRadiotherapy, AdjuvantanlotinibAntineoplastic AgentsIndolesQuinolinesAnlotinibCase reportNUT midline carcinomaPalliative radiotherapyPrimary lung tumor

Identifiers

PMID34996489
PMCPMC8742416
OpenAlexW4221120719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.