Evidence map›Paper›PMID 34996383›Full record

ArticleBMC pregnancy and childbirth2022

Psychosocial health in pregnancy and postpartum among women living with - and without HIV and non-pregnant women living with HIV living in the Nordic countries - Results from a longitudinal survey study.

Ellen Moseholm, Inka Aho, Åsa Mellgren, Gitte Pedersen, Terese L Katzenstein, Isik S Johansen, Diana Bach, Merete Storgaard, Nina Weis

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Ellen MoseholmDepartment of Infectious Diseases, Copenhagen University Hospital, Kettegård Alle 30, 2650, Hvidovre, Hvidovre, Denmark. ellen.froesig.moseholm.larsen@regionh.dk.
Inka AhoDepartment of Infectious Diseases, Helsinki University Hospital, Helsinki, Finland.
Åsa MellgrenDepartment of Infectious Diseases, Region Vestra Gotland, Sahlgrenska University Hospital, Gothenburg, Sweden.
Gitte PedersenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Terese L KatzensteinDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Isik S JohansenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Diana BachDepartment of Gynecology and Obstetrics, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark.
Merete StorgaardDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Kettegård Alle 30, 2650, Hvidovre, Hvidovre, Denmark.
Copenhagen University Hospital · DKHvidovre Hospital · DKAalborg University Hospital · DKAarhus University Hospital · DKHelsinki University Hospital · FIOdense University Hospital · DKUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe success of antiretroviral therapy has normalized pregnancy among women living with HIV (WWH) with a very low risk of perinatal transmission of HIV. Despite these advances, WWH still face complex medical and psychosocial issues during pregnancy and postpartum. The aim of this study was to assess differences in psychosocial health outcomes between pregnant WWH, non-pregnant WWH, and pregnant women without HIV, and further identify factors associated with probable depression in the third trimester and postpartum.

methodsIn a longitudinal survey study, participants were included from sites in Denmark, Finland, and Sweden during 2019-2020. Data was collected in the 3rd trimester, 3 and 6 months postpartum using standardized questionnaires assessing depression, perceived stress, loneliness, and social support. Mixed regression models were used to assess changes over time within and between groups. Logistic regression models were used to identify factors associated with depression in pregnancy and postpartum.

resultsA total of 47 pregnant WWH, 75 non-pregnant WWH, and 147 pregnant women without HIV were included. The prevalence of depression was high among both pregnant and non-pregnant WWH. There was no significant difference between pregnant and non-pregnant WWH in depression scores, perceived stress scores, or social support scores at any time point. Compared to pregnant women without HIV, pregnant WWH reported worse outcomes on all psychosocial scales. Social support and loneliness were associated with an increased odds of depressive symptoms in the adjusted analysis.

conclusionsA high burden of adverse psychosocial outcomes was observed in both pregnant and non-pregnant women living with HIV compared to pregnant women without HIV. Loneliness and inadequate social support were associated with increased odds of depression in pregnancy and should be a focus in future support interventions.

Indexed as

AdultDenmarkDepressionDepression, PostpartumFemaleFinlandHIV InfectionsHumansLogistic ModelsLonelinessLongitudinal StudiesPregnancyPregnancy Complications, InfectiousPregnant PeopleScandinavian and Nordic CountriesSocial Support2BMOMdepressionpostpartumpregnancyPsychosocial healthwomen with HIV

Identifiers

PMID34996383
PMCPMC8740861
OpenAlexW4205707213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.