Evidence map›Paper›PMID 34996361›Full record

Observational studyBMC anesthesiology2022

Geo-economic variations in epidemiology, ventilation management and outcome of patients receiving intraoperative ventilation during general anesthesia- posthoc analysis of an observational study in 29 countries.

Liselotte Hol, Sunny G L H Nijbroek, Ary Serpa Neto, Sabrine N T Hemmes, Goran Hedenstierna, Michael Hiesmayr, Markus W Hollmann, Gary H Mills, Marcos F Vidal Melo, Christian Putensen and 7 more

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01601223 (Local Assessment of Ventilatory Management During General Anesthesia for Surgery - a Prospective Observational Multi-center Cohort Study), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01601223 completednot on this map

Local Assessment of Ventilatory Management During General Anesthesia for Surgery - a Prospective Observational Multi-center Cohort Study

TypeobservationalSponsorEuropean Society of AnaesthesiologyRan2013 to 2013Enrolled10,690ConditionsSurgery, Anaesthesia, Ventilator-Induced Lung Injury, Lung Injury
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 9 countries.

Liselotte HolDepartment of Anesthesiology, Amsterdam UMC, location AMC, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands. l.hol@amsterdamumc.nl.
Sunny G L H NijbroekDepartment of Anesthesiology, Amsterdam UMC, location AMC, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Ary Serpa NetoDepartment of Intensive Care, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Sabrine N T HemmesDepartment of Anesthesiology, Amsterdam UMC, location AMC, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Goran HedenstiernaDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Michael HiesmayrDivision Cardiac, Thoracic, Vascular Anesthesia and Intensive Care, Medical University Vienna, Vienna, Austria.
Markus W HollmannDepartment of Anesthesiology, Amsterdam UMC, location AMC, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Gary H MillsOperating Services, Critical Care and Anaesthesia, Sheffield Teaching Hospitals, Sheffield and University of Sheffield, Sheffield, UK.
Marcos F Vidal MeloDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
Christian PutensenDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.
Werner SchmidDivision Cardiac, Thoracic, Vascular Anesthesia and Intensive Care, Medical University Vienna, Vienna, Austria.
Paolo SevergniniDepartment of Biotechnology and Life, ASST Sette Laghi Ospedale di Circolo e Fondazio Macchi, University of Insubria, Varese, Italy.
Hermann WriggeDepartment of Anaesthesiology, Intensive Care Medicine and Emergency Medicine, Pain Therapy, Bermannstrost Hospital Halle, Halle, Germany.
Marcelo Gama de AbreuDepartment of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics, Università degli Studi di Genova, Genova, Italy.
Marcus J SchultzDepartment of Intensive Care, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
LAS VEGAS study–investigators
Amsterdam University Medical Centers · NLMedical University of Vienna · ATBG Klinikum Bergmannstrost Halle · DECleveland Clinic · USMahidol University · THMassachusetts General Hospital · USSheffield Teaching Hospitals NHS Foundation Trust · GBUniversity Hospital Bonn · DEUniversity of Genoa · ITUniversity of Insubria · ITUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this analysis is to determine geo-economic variations in epidemiology, ventilator settings and outcome in patients receiving general anesthesia for surgery.

methodsPosthoc analysis of a worldwide study in 29 countries. Lower and upper middle-income countries (LMIC and UMIC), and high-income countries (HIC) were compared. The coprimary endpoint was the risk for and incidence of postoperative pulmonary complications (PPC); secondary endpoints were intraoperative ventilator settings, intraoperative complications, hospital stay and mortality.

resultsOf 9864 patients, 4% originated from LMIC, 11% from UMIC and 85% from HIC. The ARISCAT score was 17.5 [15.0-26.0] in LMIC, 16.0 [3.0-27.0] in UMIC and 15.0 [3.0-26.0] in HIC (P = .003). The incidence of PPC was 9.0% in LMIC, 3.2% in UMIC and 2.5% in HIC (P < .001). Median tidal volume in ml kg

conclusionThe risk for and incidence of PPC is higher in LMIC than in UMIC and HIC. Ventilation management could be improved in LMIC and UMIC.

trial registrationClinicaltrials.gov , identifier: NCT01601223.

Indexed as

AdultAgedAnesthesia, GeneralDeveloped CountriesDeveloping CountriesFemaleHumansIncidenceInternationalityIntraoperative ComplicationsLength of StayLung DiseasesMaleMiddle AgedPostoperative ComplicationsPovertyARISCAT scoreGeo–economic variationIntraoperative ventilationPostoperative pulmonary complications, ventilation, intraoperative ventilationVentilator management

Identifiers

PMID34996361
PMCPMC8740416
OpenAlexW4205243972

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.