ArticleBMC genomics2022
Comparative genome analysis of plant ascomycete fungal pathogens with different lifestyles reveals distinctive virulence strategies.
Article in BMC genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Genomic insights into adaptative traits of phyllosphere yeasts.Environmental microbiome · 2026Article
- Genomic and metabolic uniformity across diverse observed ecological contexts suggest that interactions ofIMA fungus · 2026Article
- Characterization and Genome Analysis ofJournal of fungi (Basel, Switzerland) · 2025Article
- Genomics in plant pathogen identification and control.Frontiers in plant science · 2025Review
- Comprehensive genome analysis of twoMycoKeys · 2025Article
- The Hemibiotrophic Apple Scab FungusJournal of fungi (Basel, Switzerland) · 2024Article
- Highly Repetitive Genome ofInternational journal of molecular sciences · 2024Article
- Uncovering the Mechanisms: The Role of Biotrophic Fungi in Activating or Suppressing Plant Defense Responses.Journal of fungi (Basel, Switzerland) · 2024Review
- Comparative Genomics of Fungi in Nectriaceae Reveals Their Environmental Adaptation and Conservation Strategies.Journal of fungi (Basel, Switzerland) · 2024Article
- Article
- Unravelling the Function of the Sesquiterpene Cyclase STC3 in the Lifecycle ofInternational journal of molecular sciences · 2024Article
- A microbial knowledge graph-based deep learning model for predicting candidate microbes for target hosts.Briefings in bioinformatics · 2024Article
- VirGrapher: a graph-based viral identifier for long sequences from metagenomes.Briefings in bioinformatics · 2024Article
- Comparative secretome analysis unveils species-specific virulence factors inAIMS microbiology · 2024Article
- Unveiling intraspecific diversity and evolutionary dynamics of the foodborne pathogenCurrent research in food science · 2024Article
- Applying molecular and genetic methods to trees and their fungal communities.Applied microbiology and biotechnology · 2023Review
- Draft genome sequencing ofFrontiers in microbiology · 2023Article
- Characterization ofPlants (Basel, Switzerland) · 2022Article
- Genome-Based Analysis ofBiology · 2022Article
- Genome Analyses of Two Blueberry Pathogens:Journal of fungi (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPathogens have evolved diverse lifestyles and adopted pivotal new roles in both natural ecosystems and human environments. However, the molecular mechanisms underlying their adaptation to new lifestyles are obscure. Comparative genomics was adopted to determine distinct strategies of plant ascomycete fungal pathogens with different lifestyles and to elucidate their distinctive virulence strategies.
resultsWe found that plant ascomycete biotrophs exhibited lower gene gain and loss events and loss of CAZyme-encoding genes involved in plant cell wall degradation and biosynthesis gene clusters for the production of secondary metabolites in the genome. Comparison with the candidate effectome detected distinctive variations between plant biotrophic pathogens and other groups (including human, necrotrophic and hemibiotrophic pathogens). The results revealed the biotroph-specific and lifestyle-conserved candidate effector families. These data have been configured in web-based genome browser applications for public display ( http://lab.malab.cn/soft/PFPG ). This resource allows researchers to profile the genome, proteome, secretome and effectome of plant fungal pathogens.
conclusionsOur findings demonstrated different genome evolution strategies of plant fungal pathogens with different lifestyles and explored their lifestyle-conserved and specific candidate effectors. It will provide a new basis for discovering the novel effectors and their pathogenic mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.