Evidence map›Paper›PMID 34996130›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2022

Relationships between tendon structure and clinical impairments in patients with patellar tendinopathy.

Andrew L Sprague, Christian Couppé, Ryan T Pohlig, Daniel C Cortes, Karin Grävare Silbernagel

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Reliability and Repeatability of Diffusion Tensor Imaging in Healthy and Pathological Patellar Tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Challenging the assumption of uniformity in patellar tendon structure: Regional patellar tendon morphology and mechanical properties in vivo.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  8. Reliability of Continuous Shear Wave Elastography in the Pathological Patellar Tendon.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2023
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Andrew L SpragueDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.ORCID 0000-0001-6764-057X
Christian CouppéDepartment of Orthopaedic Surgery M, Faculty of Health and Medical Sciences, Institute of Sports Medicine Copenhagen, Bispebjerg Hospital and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1648-5746
Ryan T PohligBiostatistic Core Facility, College of Health Sciences, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-8385-8218
Daniel C CortesDepartment of Mechanical Engineering, Penn State University, State College, Pennsylvania, USA.
Karin Grävare SilbernagelDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.ORCID 0000-0001-7566-407X
University of Delaware · USPennsylvania State University · USUniversity of Copenhagen · DKUniversity of Pittsburgh · US

Funding

PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
Recovery of symptoms, function, tendon structure and mechanical properties in patients with Achilles Tendinopathy: A comparison between men and womenR01AR072034 · NIAMS · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2018 to 2022
$2.5M
NIAMS NIH HHS R01 AR072034NICHD NIH HHS T32 HD007490
6 · The paper itself

Abstract

The clinical relevance of altered tendon structure in patellar tendinopathy is contested since structural change persists after symptom resolution. The purpose of this study was to explore the relationships between tendon structure and clinical impairments in patellar tendinopathy. In this retrospective, secondary analysis of individuals with patellar tendinopathy (n = 41), tendon structure (thickness, cross-sectional area [CSA], shear modulus, and viscosity), symptom severity, lower extremity function (counter-movement jump [CMJ] height), and quadriceps muscle performance (knee extension force and central activation ratio [CAR]) were recorded for the symptomatic limb. Relationships among structure, symptom severity, lower extremity function, and quadriceps muscle performance were examined using sequential regression models. Adjusting for age, sex, body mass index, and pain levels, there were significant positive relationships for thickness (p < 0.001, β = 0.718) and viscosity (p = 0.006, β = 0.496) with CMJ height. There were significant negative relationships between CSA with both CMJ height (p = 0.001, β = -0.538) and CAR (p = 0.04, β = -0.517). This is the first study to demonstrate relationships between tendon structure and lower extremity function or quadriceps muscle performance in patients with patellar tendinopathy. Clinical significance: Since structural changes persist after symptom resolution, addressing these changes may assist in restoring lower extremity function and quadriceps muscle performance.

Indexed as

Musculoskeletal DiseasesPatellar LigamentTendinopathyHumansKnee JointRetrospective StudiesTendonsjumper's kneemechanical propertiesmorphologypatellar tendinopathyultrasound elastography

Identifiers

PMID34996130
PMCPMC9259765
OpenAlexW4206561240

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.