Evidence map›Paper›PMID 34995684›Full record

ArticleJournal of pain and symptom management2022

Palliative and End-of-Life Care After Severe Stroke.

Amber R Comer, Linda S Williams, Stephanie Bartlett, Lynn D'Cruz, Katlyn Endris, McKenzie Marchand, Isabel Zepeda, Sumeet Toor, Carly Waite, Areeba Jawed and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of pain and symptom management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Validation of the Charlotte large artery occlusion endovascular therapy outcome score using Viz.ai-derived cerebral blood volume index.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. End-of-Life Care in an Acute Neurological Ward: A Retrospective Analysis of Clinical Practices During the Last Week of Life.The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Amber R ComerIndiana University School of Health and Human Sciences (A.R.C), Indianapolis, Indiana. Electronic address: comer@iu.edu.
Linda S WilliamsRichard L. Roudebush Veterans Affairs Medical Hospital (L.S.W), Indiana University School of Medicine, Regenstrief Institute, Inc, Indianapolis, Indiana, USA.
Stephanie BartlettIndiana University School of Health and Human Sciences (S.B., L.D., K.E., M.M., I.Z., C.W.), Indianapolis, Indiana, USA.
Lynn D'CruzIndiana University School of Health and Human Sciences (S.B., L.D., K.E., M.M., I.Z., C.W.), Indianapolis, Indiana, USA.
Katlyn EndrisIndiana University School of Health and Human Sciences (S.B., L.D., K.E., M.M., I.Z., C.W.), Indianapolis, Indiana, USA.
McKenzie MarchandIndiana University School of Health and Human Sciences (S.B., L.D., K.E., M.M., I.Z., C.W.), Indianapolis, Indiana, USA.
Isabel ZepedaIndiana University School of Health and Human Sciences (S.B., L.D., K.E., M.M., I.Z., C.W.), Indianapolis, Indiana, USA.
Sumeet ToorIndiana University School of Medicine (S.T., J.E.S.), Indianapolis, Indiana, USA.
Carly WaiteIndiana University School of Health and Human Sciences (S.B., L.D., K.E., M.M., I.Z., C.W.), Indianapolis, Indiana, USA.
Areeba JawedUniversity Of Michigan (A.J.), Ann Arbor, Michigan, USA.
Robert HollowayUniversity of Rochester (R.H.), Rochester, New York, USA.
Claire J CreutzfeldtUniversity of Washington (C.J.W.), Seattle, Washington, USA.
James E SlavenIndiana University School of Medicine (S.T., J.E.S.), Indianapolis, Indiana, USA.
Alexia M TorkeIndiana University School of Medicine, Indiana University Center for Aging Research, Regenstrief Institute (A.M.T.), Daniel F. Evans Center for Spiritual and Religious Values in Healthcare, Indianapolis, Indiana, USA.
Indiana University Health · USIndiana University – Purdue University Indianapolis · USRegenstrief Institute · USRichard L. Roudebush VA Medical Center · USUniversity of Michigan · USUniversity of Rochester · USUniversity of Washington · US

Funding

Understanding the needs and experiences of surrogate decision makers caring for SGM individuals with Alzheimer's Disease and Related Dementias.K24AG053794 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI TORKE, ALEXIA MARY · 2016 to 2025
$1.8M
Which palliative care quality measures improve patient-centered outcomes?K08HS023681 · AHRQ · DUKE UNIVERSITY · PI KAMAL, ARIF · 2015 to 2019
$733k
NIA NIH HHS K24 AG053794
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe distinct illness trajectory after acute ischemic stroke demands a better understanding of the utilization of palliative care consultations (PCC) for this patient cohort. This study sought to determine the prevalence, predictors, and outcomes associated with PCC for patients hospitalized with severe ischemic stroke.

methodsThis multicenter cohort study was conducted at four hospitals (2 comprehensive and 2 primary stroke centers) between January, 2016 and December, 2019. We included all patients with a discharge diagnosis of ischemic stroke and an initial National Institutes of Health Stroke Scale (NIHSS) of 10 or greater. We compared patient sociodemographic, clinical and care characteristics as well as hospital outcomes between patients who did and did not receive PCC.

resultsThe study included 1297 patients hospitalized with severe ischemic stroke. PCC occurred for 20% of all patients and this proportion varied across institutions from 11.9% to 43%. Less than half (43%) of patients who died in the hospital. In multivaraible analysis, PCC was less likely in female patients (OR .76, 95% CI .59, .99, P=0.04) but more likely in patients with higher NIHSS (OR1.95, 95% CI 1,13, 3.37, P=0.02). Patients with PCC had higher rates of moving to a plan focused on comfort measures (CMO) (P<0.01) and removal of artificial nutrition as part of a move to CMO (P<0.01). In a sub analysis of patients who died in the hospital and received PCC, patients who died on or before hospital day 3 were less likely to receive PCC than patients who died on or after hospital day 4 (24% v. 51%) (P=<0.01).

conclusionsMost patients with severe stroke do not receive PCC, even among those who experience in-hospital death. The results of this study indicate there are missed opportunities for PCC to help reduce suffering after severe stroke.

Indexed as

Ischemic StrokeStrokeTerminal CareCohort StudiesFemaleHospital MortalityHumansPalliative CareRetrospective Studiesend-of-lifePalliative Carestroke

Identifiers

PMID34995684
PMCPMC9018507
OpenAlexW4206577567

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.