Evidence map›Paper›PMID 34994882›Full record

ArticleThe international journal of cardiovascular imaging2022

Normal ranges of left atrial volumes and ejection fraction by 3D echocardiography in adults: a systematic review and meta-analysis.

Stefano Figliozzi, Georgios Georgiopoulos, Kostantinos Pateras, Alexandros Sianis, Marco Previtero, Lara Tondi, Ιoannis Petropoulos, Renato Maria Bragato, Alexandros Papachristidis, Gianluigi Condorelli and 1 more

Abstract read
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In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. The use of cardiac imaging in patients undergoing atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 5 countries.

Stefano FigliozziClinical Echocardiography Diagnostic Service, Cardio Center, Humanitas Research Hospital IRCCS, Via Alessandro Manzoni, 56, 20089, Rozzano, MI, Italy. stefanofigliozzi@hotmail.it.ORCID http://orcid.org/0000-0003-2991-1548
Georgios GeorgiopoulosDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.
Kostantinos PaterasDepartment of Biostatistics, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Alexandros SianisDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.
Marco PreviteroCardiology Unit, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Lara TondiMultimodality Imaging Section IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Ιoannis PetropoulosDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.
Renato Maria BragatoClinical Echocardiography Diagnostic Service, Cardio Center, Humanitas Research Hospital IRCCS, Via Alessandro Manzoni, 56, 20089, Rozzano, MI, Italy.
Alexandros PapachristidisKing's College Hospital, NHS Foundation Trust, London, UK.
Gianluigi CondorelliClinical Echocardiography Diagnostic Service, Cardio Center, Humanitas Research Hospital IRCCS, Via Alessandro Manzoni, 56, 20089, Rozzano, MI, Italy.
Masaaki TakeuchiDepartment of Laboratory and Transfusion Medicine, Hospital of University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan.
IRCCS Humanitas Research Hospital · ITNational and Kapodistrian University of Athens · GRHumanitas University · ITIRCCS Policlinico San Donato · ITKing's College Hospital NHS Foundation Trust · GBKing's College London · GBUniversity of Occupational and Environmental Health Japan · JPUniversity of Padua · ITUniversity of Thessaly · GR

Funding

Alexander S. Onassis Public Benefit Foundation Special grantAlexander S. Onassis Public Benefit Foundation support program for scholars' association members (GRANT No. R ZP 001/2019-2020)European Association of Cardiovascular Imaging (EACVI) Training grant 2021
6 · The paper itself

Abstract

Increased sizes and dysfunction of the left atrium have been related to adverse outcomes. 3D-echocardiography is more accurate than 2D-echocardiography in estimating LA volumes and ejection fraction. However, the use of 3DE for LA analysis is limited by the absence of established reference values. We performed a systematic review and meta-analysis to provide reference ranges of LA maximum and minimum volumes indexed for body surface area (LAVi max and LAVi min, respectively), and LA-EF assessed by 3DE in healthy adults. Data search was conducted from inception through September 15, 2021, using the following Medical Subject Heading terms: left atrial/atrium, three-dimensional/3D echocardiography. The study protocol was registered in the PROSPERO database (CRD42021252428). 15 studies including 4,226 healthy adults (51% males) and reporting 3DE values of LAVi max, LAVi min and LA-EF were selected. LAVi max, LAVi min and LA-EF mean and reference values were equal to 25.18 ml/m

Indexed as

3D-echocardiographyEjection fractionLeft atriumNormal valuesThree-dimensional echocardiographyVolume

Identifiers

PMID34994882
OpenAlexW4205355944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.