Evidence map›Paper›PMID 34994646›Full record

ArticleJCO precision oncology2021

Tumor Growth Rate After Nadir Is Associated With Survival in Patients With

Mizuki Nishino, Junwei Lu, Takuya Hino, Natalie I Vokes, Pasi A Jänne, Hiroto Hatabu, Bruce E Johnson

Open access · greenAbstract read
In one paragraph

Article in JCO precision oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Dissecting sources of variability in patient response to targeted therapy: anti-HER2 therapies as a case study.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mizuki NishinoDepartment of Imaging, Dana Farber Cancer Institute, Boston, MA.ORCID 0000-0003-0275-0502
Junwei LuDepartment of Biostatistics, Harvard Chan School of Public Health, Boston, MA.
Takuya HinoDepartment of Radiology, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0002-8225-0737
Natalie I VokesDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, MA.ORCID 0000-0002-3766-5335
Pasi A JänneDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, MA.ORCID 0000-0002-7821-4928
Hiroto HatabuDepartment of Imaging, Dana Farber Cancer Institute, Boston, MA.ORCID 0000-0003-1436-2988
Bruce E JohnsonDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, MA.ORCID 0000-0002-5252-3677
Brigham and Women's Hospital · USHarvard University · US

Funding

The Boston Lung Cancer Survival CohortU01CA209414 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI David C Christiani · 2017 to 2026
$12.2M
Automated in vivo analysis of tumor growth rate as a guide for therapeutic decisions to advance personalized cancer treatmentR01CA203636 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI NISHINO, MIZUKI · 2017 to 2021
$2.9M
NCI NIH HHS R01 CA203636NCI NIH HHS U01 CA209414
6 · The paper itself

Abstract

purposeTo investigate the association between tumor volume growth rate after the nadir and survival in patients with MATERIALS AND

methodsSeventy-one patients with

resultsThe median tumor volume for the cohort was 19,842 mm

conclusionIn patients with

Indexed as

AdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungCohort StudiesErbB ReceptorsErlotinib HydrochlorideFemaleHumansLung NeoplasmsMaleMiddle AgedMutationProtein Kinase InhibitorsSurvival RateTumor BurdenEGFR protein, humanErbB ReceptorsErlotinib HydrochlorideProtein Kinase Inhibitors

Identifiers

PMID34994646
PMCPMC9848598
OpenAlexW3207474101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.