Evidence map›Paper›PMID 34994484›Full record

ArticleJournal of veterinary internal medicine2022

Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs.

Rory Fentem, Alberta de Stefani, Rodrigo Gutierrez Quintana, Emili Alcoverro, Gareth Michael Couper Jones, Pablo Amengual-Batle, Rita Gonçalves

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rory FentemSmall Animal Teaching Hospital, School of Veterinary Science, University of Liverpool, Neston, United Kingdom.ORCID https://orcid.org/0000-0001-5094-7831
Alberta de StefaniQueen Mother Hospital for Animals, Royal Veterinary College, University of London, Hertfordshire, United Kingdom.
Rodrigo Gutierrez QuintanaSmall Animal Hospital, School of Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-3570-2542
Emili AlcoverroChestergates Veterinary Specialists, Cheshire, United Kingdom.
Gareth Michael Couper JonesQueen Mother Hospital for Animals, Royal Veterinary College, University of London, Hertfordshire, United Kingdom.
Pablo Amengual-BatleSmall Animal Hospital, School of Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom.
Rita GonçalvesSmall Animal Teaching Hospital, School of Veterinary Science, University of Liverpool, Neston, United Kingdom.ORCID https://orcid.org/0000-0001-5420-9801
Royal Veterinary College · GBUniversity of Glasgow · GBUniversity of Liverpool · GBCheshire West and Chester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStatus epilepticus (SE) is an emergency associated with serious consequences for both patient and owner. Data regarding risk factors for short-term mortality or recurrence in dogs with SE is limited.

objectiveIdentify risk factors associated with short-term mortality (euthanasia or spontaneous death) and recurrence of SE in dogs. ANIMALS: One hundred twenty-four client-owned dogs that sustained an episode of SE.

methodsRetrospective multicenter study using data collected from medical records of dogs presented in SE to the contributing institutions. Multivariable logistic regression analysis was performed using a manual backwards stepwise approach to identify risk factors associated with short-term mortality and recurrence of SE after discharge.

resultsShort-term mortality for affected dogs was 29.8%. Factors significantly associated with short-term mortality included increased patient age, shorter duration of hospitalization, development of SE before arrival, and SE caused by a potentially fatal etiology. Status epilepticus recurred in 27% of dogs that survived to discharge. Factors significantly associated with recurrence of SE included prior history of pharmacoresistant epilepsy and predominance of a focal seizure phenotype. CONCLUSIONS AND CLINICAL IMPORTANCE: Our results may be used to inform clinicians and dog owners regarding risk factors for both short-term mortality and recurrence in dogs with SE.

Indexed as

Dog DiseasesStatus EpilepticusAnimalsAnticonvulsantsDogsRetrospective StudiesRisk FactorsAnticonvulsantscanineepilepsyoutcomeseizures

Identifiers

PMID34994484
PMCPMC8965210
OpenAlexW4205751136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.