Evidence map›Paper›PMID 34993946›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Metabolic Imaging Using Hyperpolarization for Assessment of Premalignancy.

Shivanand Pudakalakatti, Priyank Raj, Travis C Salzillo, José S Enriquez, Dontrey Bourgeois, Prasanta Dutta, Mark Titus, Shayan Shams, Priya Bhosale, Michael Kim and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shivanand Pudakalakatti *Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Priyank Raj *Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Travis C SalzilloDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
José S EnriquezDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dontrey BourgeoisDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Prasanta DuttaDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mark TitusDepartment of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shayan ShamsDepartment of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, USA.
Priya BhosaleMD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX, USA.
Michael KimMD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX, USA.
Florencia McAllisterMD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX, USA.
Pratip K BhattacharyaDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA. pkbhattacharya@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USThe University of Texas Health Science Center at Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
WU-MDACC Inter-Institutional Molecular Imaging CenterP50CA094056 · NCI · WASHINGTON UNIVERSITY · PI PIWNICA-WORMS, DAVID · 2002 to 2016
$26.3M
Texas Center for Cancer NanomedicineU54CA151668 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FERRARI, MAURO · 2010 to 2014
$12.4M
Circulating Biomarkers and Imaging for Early Detection of Pancreatic CancerU01CA214263 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI EUGENE J KOAY, Subrata Sen · 2018 to 2026
$7.2M
Training Program in Biostatistics for Cancer ResearchT32CA096520 · NCI · RICE UNIVERSITY · PI KIMMEL, MAREK, YUAN, YING · 2003 to 2023
$4.5M
Translational Applications in an Animal Model of Pancreatic Cystic Neoplasm and CancerR01CA218004 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MAITRA, ANIRBAN · 2018 to 2021
$2.4M
Targeted Hyperpolarized Molecular Beacons for Colorectal Cancer DetectionR21EB031217 · NIBIB · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BHATTACHARYA, PRATIP K. · 2021 to 2023
$648k
(PQC5)Early Detection Pancreatic Cancer by Hyperpolarized Silicon NanoparticlesR21CA185536 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BHATTACHARYA, PRATIP K. · 2014 to 2015
$383k
MURINE MONOCLONAL ANTIBODIES TO HUMAN RESPIRATORY GLYCOPROTEINZ01CL000021 · CLC · CLINICAL CENTER · PI SHELHAMER, J H · 1987 to 1988
–
CLC NIH HHS 75N90019D00021NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA094056NCI NIH HHS R01 CA218004NCI NIH HHS R21 CA185536NCI NIH HHS T32 CA096520NCI NIH HHS U01 CA214263NCI NIH HHS U54 CA151668NIBIB NIH HHS R21 EB031217ORFDO NIH HHS 75N99019D00021
6 · The paper itself

Abstract

There is an unmet need for noninvasive surrogate markers that can help identify premalignant lesions across different tumor types. Here we describe the methodology and technical details of protocols employed for in vivo

Indexed as

Precancerous ConditionsPyruvic AcidCarbon IsotopesHumansMagnetic Resonance ImagingCarbon IsotopesPyruvic Acid13CAssessment of preventive responsesEarly detectionHP-MRHyperpolarizationMetabolic imagingMRIPremalignancy

Identifiers

PMID34993946
PMCPMC9352438
OpenAlexW4205578040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.