Evidence map›Paper›PMID 34993863›Full record

Trial reportJournal of general internal medicine2022

Health Within Reach-a Patient-Centered Intervention to Increase Hepatitis B Screening Among Asian Americans: a Randomized Clinical Trial.

Mandana Khalili, Nicole J Kim, Janice Y Tsoh, Judith M E Walsh, L Elizabeth Goldman, Ginny Gildengorin, Ching Wong, Mi T Tran, Edgar Yu, Michael Thanh Sharp and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02139722 (A Patient-Centered Intervention to Increase Screening of Hepatitis B and C Among Asian Americans), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02139722 nacompletednot on this map

A Patient-Centered Intervention to Increase Screening of Hepatitis B and C Among Asian Americans

TypeinterventionalSponsorUniversity of California, San FranciscoRan2014 to 2017Enrolled431ConditionsHepatitis B, Hepatitis C, Liver DiseaseArmsVideo Doctor, PA + PPN
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Exploring the Psychosocial Influences on Hepatitis B and Liver Cancer Disparities.Journal of racial and ethnic health disparities · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mandana KhaliliDivision of Gastroenterology and Hepatology, University of California San Francisco, San Francisco, CA, USA. Mandana.Khalili@ucsf.edu.
Nicole J KimDivision of Gastroenterology, University of Washington, Seattle, WA, USA.ORCID 0000-0003-2348-0580
Janice Y TsohDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA.
Judith M E WalshDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
L Elizabeth GoldmanDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Ginny GildengorinDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Ching WongDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Mi T TranDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Edgar YuDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA.
Michael Thanh SharpDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Vivian H LeTranDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Vi-Van NguyenDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.
Tung T NguyenDivision of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.

Funding

UNIVERSITY OF WASHINGTON GI TRAINING GRANTT32DK007742 · NIDDK · UNIVERSITY OF WASHINGTON · PI GRADY, WILLIAM MALLORY · 1996 to 2022
$4.7M
Mentoring Multidisciplinary Patient-Oriented Research in Viral HepatitisK24AA022523 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KHALILI, MANDANA · 2013 to 2023
$1.9M
NIAAA NIH HHS K24 AA022523NIDDK NIH HHS T32 DK007742
6 · The paper itself

Abstract

backgroundThere are few studies to date of interventions to increase viral hepatitis screening among Asian Americans, who have high rates of chronic hepatitis B (HBV) infection.

objectiveTo develop, implement, and test the efficacy of a mobile application (Hepatitis App) delivered in four languages to increase HBV screening among Asian Americans.

designCluster-randomized clinical trial.

participantsFour hundred fifty-two Asian American patients ≥ 18 years of age, who had no prior HBV testing, and received primary care within two healthcare systems in San Francisco, CA.

interventionsThe intervention group received the Hepatitis App, delivering interactive video education on viral hepatitis in English, Cantonese, Mandarin, or Vietnamese and a provider printout (Provider Alert) and Provider Panel Notification. The comparison group received a mobile application delivering nutrition and physical activity education and Provider Panel Notification. MAIN MEASURES: Primary outcomes were patient-provider discussion about HBV and documentation of a HBV screening test within 3 months post-intervention. Secondary outcome was documentation of an order for a HBV screening test. KEY

resultsParticipants had a mean age of 57 years and were 64% female, 80% foreign-born, and 44% with limited English fluency. At post-visit, over 80% of intervention participants reported they liked using the Hepatitis App. At 3-month follow-up, the intervention group was more likely than the comparison group (all P < 0.001) to have discussed HBV with their provider (70% vs.16%), have a HBV test ordered (44% vs.10%), and receive a HBV test (38% vs.8%). In multivariable analyses, the intervention odds ratio for HBV test ordering was 7.6 (95% CI: 3.9, 14.8) and test receipt was 7.5 (95% CI: 3.6, 15.5).

conclusionsA multi-lingual educational intervention using a mobile application in primary care clinics was well received by Asian American patients, enhanced patient-provider communication about HBV, and increased HBV screening. Technology can improve healthcare quality among Asian Americans.

trial registrationClinicalTrials.gov NCT02139722 ( https://clinicaltrials.gov/ct2/show/NCT02139722 ).

Indexed as

AsianHepatitis BFemaleHumansMaleMass ScreeningMiddle AgedOdds RatioPatient-Centered CareHealthcare disparitiesLanguageMobile technologyPrimary careViral hepatitis

Identifiers

PMID34993863
PMCPMC9550928

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.