Evidence map›Paper›PMID 34993756›Full record

ArticleJournal of cardiovascular translational research2022

Ferulic Acid Alleviates Atherosclerotic Plaques by Inhibiting VSMC Proliferation Through the NO/p21 Signaling pathway.

Xiaoyun Wu, Ziwei Hu, Junjie Zhou, Jin Liu, Ping Ren, Xi Huang

Open access · hybridAbstract read
In one paragraph

Article in Journal of cardiovascular translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. Nutrition research and practice · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiaoyun WuMedical College, Xiamen University, Xiamen, 361102, China.
Ziwei HuSchool of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, China.
Junjie ZhouSchool of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, China.
Jin LiuMedical College, Xiamen University, Xiamen, 361102, China.
Ping RenInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, 138 Xianlin Rd., 210023, Nanjing, China.
Xi HuangMedical College, Xiamen University, Xiamen, 361102, China. 290606@njucm.edu.cn.ORCID 0000-0003-0306-1127
Nanjing University of Chinese Medicine · CNXiamen University · CNGannan Medical University · CN

Funding

the Fund for 985 Construction of Medical College of Xiamen University 0070-Z03101the National Natural Science Foundation of China 81173591the National Natural Science Foundation of China 81373855
6 · The paper itself

Abstract

The benefits and risks of inhibiting the proliferation and migration of vascular smooth muscle cells (VSMCs) in atherosclerosis (AS) remain a subject of debate. In this study, we investigated the effect of ferulic acid (FA) on the proliferation and migration of VSMCs induced by platelet-derived growth factor (PDGF) and the associated mechanism and used ApoE

Indexed as

AtherosclerosisPlaque, AtheroscleroticAnimalsCell MovementCell ProliferationCells, CulturedCoumaric AcidsMiceMuscle, Smooth, VascularMyocytes, Smooth MuscleSignal TransductionCoumaric Acidsferulic acidAtherosclerosisFerulic acidNO/p21VSMC

Identifiers

PMID34993756
PMCPMC9622559
OpenAlexW4205237107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.