Evidence map›Paper›PMID 34993755›Full record

ArticleJournal of natural medicines2022

Phytochemical investigation of the fruits of Xanthium strumarium and their cytotoxic activity.

Xiang-Wei Xu, Yi-Yuan Xi, Jun Chen, Feng Zhang, Ju-Jia Zheng, Peng-Hai Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of natural medicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiang-Wei XuDepartment of Pharmacy, The First People's Hospital of Yongkang Affiliated To Hangzhou Medical College, Yongkang, 321300, China.
Yi-Yuan XiSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Jun ChenDepartment of Pharmacy, The First People's Hospital of Yongkang Affiliated To Hangzhou Medical College, Yongkang, 321300, China.
Feng ZhangDepartment of Oncology, Yongkang Hospital of Traditional Chinese Medicine, Yongkang, 321300, People's Republic of China.
Ju-Jia ZhengSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Peng-Hai ZhangDepartment of Oncology, Yongkang Hospital of Traditional Chinese Medicine, Yongkang, 321300, People's Republic of China. zhangpenghaiph@163.com.
Anyang Hospital of Traditional Chinese Medicine · CNHangzhou Medical College · CNWenzhou Medical University · CN

Funding

Chinese Medicine Science and Technology Program of Zhejiang Province 2021ZB324
6 · The paper itself

Abstract

Eight pentacyclic triterpenoids including two new ones (1, 2) were isolated from the fruits of Xanthium strumarium. Their structures were elucidated by extensive spectroscopic analysis. All isolates were evaluated for in vitro cytotoxic activity on HepG2, A549, HCT116 and SW480 cancer cells. Among them, the new compound 2 was found to exhibit significant cytotoxic activity on A549, HCT116 and SW480 cancer cells with IC

Indexed as

Antineoplastic AgentsXanthiumFruitPhytochemicalsAntineoplastic AgentsPhytochemicalsCompositaeCytotoxic activityTriterpenoidsXanthium strumarium

Identifiers

PMID34993755
OpenAlexW4206518864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.