Evidence map›Paper›PMID 34993696›Full record

ArticleAnnals of biomedical engineering2022

Quantifying Tumor and Vasculature Deformations during Laryngoscopy.

Xiaotian Wu, David A Pastel, Rihan Khan, Clifford J Eskey, Yuan Shi, Michael Sramek, Joseph A Paydarfar, Ryan J Halter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaotian WuGordon Center for Medical Imaging at Massachusetts General Hospital and Harvard Medical School, 13th St, CNY149-5212, Charlestown, MA, 02129, USA. Xwu23@mgh.harvard.edu.ORCID http://orcid.org/0000-0003-3178-6256
David A PastelDepartment of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.
Rihan KhanDepartment of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.
Clifford J EskeyDepartment of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.
Yuan ShiThayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Michael SramekGeisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.
Joseph A PaydarfarGeisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.
Ryan J HalterGeisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.

Funding

SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
NCATS NIH HHS L30 TR001096NCATS NIH HHS UL1 TR001086NCATS NIH HHS UL1TR001096NIBIB NIH HHS T32 EB013180NIBIB NIH HHS T32EB013180
6 · The paper itself

Abstract

Retractors and scopes used in head and neck surgery to provide adequate surgical exposure also deform critical structures in the region. Surgeons typically use preoperative imaging to plan and guide their tumor resections, however the large tissue deformation resulting from placement of retractors and scopes reduces the utility of preoperative imaging as a reliable roadmap. We quantify the extent of tumor and vasculature deformation in patients with tumors of the larynx and pharynx undergoing diagnostic laryngoscopy. A mean tumor displacement of 1.02 cm was observed between the patients' pre- and intra-operative states. Mean vasculature displacement at key bifurcation points was 0.99 cm. Registration to the hyoid bone can reduce tumor displacement to 0.67 cm and improve carotid stem angle deviations but increase overall vasculature displacement. The large deformation results suggest limitations in reliance on preoperative imaging and that using specific landmarks intraoperatively or having more intraoperative information could help to compensate for these deviations and ultimately improve surgical success.

Indexed as

LarynxNeoplasmsHumansLaryngoscopyMicrosurgeryPharynxIntraoperative deformationLaryngeal cancerTransoral surgeryTumor deformationVasculature deformation

Identifiers

PMID34993696
PMCPMC9035291

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.