Evidence map›Paper›PMID 34993589›Full record

ArticleSurgical endoscopy2022

Is the use of fully covered metal stents effective in the treatment of difficult lithiasis of the common bile duct?

Giuseppe Grande, Flavia Pigò, Luciana Avallone, Helga Bertani, Santi Mangiafico, Salvatore Russo, Silvia Cocca, Marinella Lupo, Angelo Caruso, Rita Conigliaro

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Giuseppe GrandeAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Flavia PigòAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy. flaviapigo@virgilio.it.ORCID http://orcid.org/0000-0002-0917-0802
Luciana AvalloneAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Helga BertaniAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Santi MangiaficoAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Salvatore RussoAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Silvia CoccaAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Marinella LupoAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Angelo CarusoAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Rita ConigliaroAzienda Ospedaliero-Universitaria di Modena Policlinico di Modena, Viale Giardini 1355, 41126, Modena, Italy.
Azienda Ospedaliero-Universitaria di Modena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of difficult lithiasis of common bile duct (CBD) often requires a multimodal approach. Fully Covered Metal Stents (FCSEMS) could fragment the stones, dilate strictures of the CBD and progressively enlarge the papillary orifice. The aim of the study was to evaluate the efficacy of FCSEMS in the treatment of difficult lithiasis of CBD.

methodsAll consecutive cases of difficult lithiasis of CBD after an attempt of clearance with complete sphincterotomy were retrospectively considered from 2009 to 2019. Intrahepatic lithiasis cases were excluded. Multivariable analysis (stepwise logistic regression if p value < 0.1 at univariable analysis) was made to understand factors associated with efficacy of FCSEMS in difficult lithiasis of CBD.

results163 cases of difficult lithiasis over 1516 cases of lithiasis of CBD (incidence of 11%) were considered. Among eligible patients, 96 (mean age 78 ± 11.9 years, 43% males) placed a FCSEMS during the first ERCP. Mean diameter of stone was 17.5 ± 5.5 mm. An attempt of dilation during the same procedure was made in 18% cases. After removal of the stent, 52 (54%) patients had complete clearance of CBD at cholangiography. The rest of patients (44), subsequently underwent multimodal treatment (final success of 95%). After logistic regression, variables positively associated with clearance of CBD were sex male (OR 3.5) and stent permanence ≥ 30 days (OR 3.2). Diameter of the stone ≥ 2 cm was associated with failure (OR 0.2). 7 post-ERCP pancreatitis, 6 post-sphincterotomy bleeding and 3 cholangitis occurred.

conclusionsFCSEMS are useful in the approach of difficult lithiasis of CBD with no significant adverse events associated.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeLithiasisAgedAged, 80 and overCommon Bile DuctFemaleHumansMaleRetrospective StudiesStentsTreatment OutcomeBiliaryERCPLithiasisStent

Identifiers

PMID34993589
OpenAlexW4205921581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.