Evidence map›Paper›PMID 34993436›Full record

ArticleCJC open2021

Sex and Medium-term Outcomes of ST-Segment Elevation Myocardial Infarction in Kerala, India: A Propensity Score-Matched Analysis.

Anoop Mathew, Yongzhe Hong, Haran Yogasundaram, Jeevan Nagendran, Eapen Punnoose, S M Ashraf, Louie Fischer, Jabir Abdullakutty, Sunil Pisharody, Kevin Bainey and 1 more

Open access · goldAbstract read
In one paragraph

Article in CJC open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Anoop MathewDivision of Cardiology, University of Alberta Hospital, Edmonton, Alberta, Canada.
Yongzhe HongDivision of Cardiac Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada.
Haran YogasundaramDivision of Cardiology, University of Alberta Hospital, Edmonton, Alberta, Canada.
Jeevan NagendranDivision of Cardiac Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada.
Eapen PunnooseDivision of Cardiology, Malankara Orthodox Syrian Christian Medical College Hospital, Kolenchery, Kerala, India.
S M AshrafDivision of Cardiology, Government Medical College Hospital, Pariyaram, Kerala, India.
Louie FischerDivision of Cardiology, Malankara Orthodox Syrian Christian Medical College Hospital, Kolenchery, Kerala, India.
Jabir AbdullakuttyDivision of Cardiology, Lisie Hospital, Kochi, Kerala, India.
Sunil PisharodyDivision of Cardiology, Elamkulam Manakkal Sankaran Memorial Co-operative Hospital and Research Centre, Perinthalmanna, Kerala, India.
Kevin BaineyDivision of Cardiology, University of Alberta Hospital, Edmonton, Alberta, Canada.
Michelle GrahamDivision of Cardiology, University of Alberta Hospital, Edmonton, Alberta, Canada.
Alberta Hospital Edmonton · CAChristian Medical College · INUniversity of Alberta Hospital · CAChristian Medical College & Hospital · INGeneral Hospital Ernakulam · INGovernment Medical College and Hospital · INLourdes Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSex-based differences have been found in outcomes following ST-segment myocardial infarction (STEMI). Studies assessing sex-based differences in STEMI among Indian patients have reported conflicting results.

methodsA prospective multicenter registry of consecutive patients with STEMI who presented to percutaneous coronary intervention (PCI)-capable hospitals in the Indian state of Kerala between June 2013 and March 2017 was used to assess 1-year outcomes. The primary endpoint was a composite of major adverse cardiac events (MACE), including death, stroke, nonfatal myocardial infarction, and rehospitalization for heart failure. Outcomes of 2 sex-based propensity score-matched groups were compared.

resultsWe included 3194 patients (19.4% women). Women presenting with STEMI were older, had more traditional cardiovascular risk factors, and were more likely to be classified as living in poverty. After propensity-score matching, women experienced greater incidence of MACE (20.9% vs 14.3%,

conclusionsWomen in this cohort experienced higher incidence of MACE at 1 year, compared to men, primarily owing to increased mortality. Timeliness of reperfusion appears to be the primary factor impacting differences in outcomes between the 2 groups and may represent an attractive target for quality-improvement initiatives.

Identifiers

PMID34993436
PMCPMC8712709
OpenAlexW3203651793

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.