ArticleCJC open2021
Symptom Presentation and Access to Medical Care in Patients With Postural Orthostatic Tachycardia Syndrome: Role of Sex.
Article in CJC open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Observational
- Long-term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow-up of over 20 years.Journal of internal medicine · 2026Article
- Cardiovascular Health in Women-Across the Lifespan.Clinical endocrinology · 2026Review
- The body and the brain keep the score: a data-driven conceptual model linking trauma and postural tachycardia syndrome.Frontiers in psychology · 2026Review
- Long-Term Postural Orthostatic Tachycardia Syndrome Outcomes Survey: Educational, Economic, and Social Impact.Journal of the American Heart Association · 2025Article
- Long-COVID and postural orthostatic tachycardia syndrome: a preliminary comparison of neuropsychological performance.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- The Long-Term Postural Orthostatic Tachycardia Syndrome Outcomes Survey-Gynecologic Findings: A Cross-Sectional Survey in Young Women.Obstetrics and gynecology international · 2025Article
- Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study.Pilot and feasibility studies · 2023Article
- Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundPostural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily impacts female patients of childbearing age. The role of sex differences in POTS is not well understood. We sought to identify sex differences in diagnosis, symptoms, comorbidities, and treatments in female and male patients diagnosed with POTS.
methodsA comprehensive survey was designed in partnership by Dysautonomia International (East Moriches, NY) and Vanderbilt University Medical Center (Nashville, TN). Patients were recruited through Dysautonomia International's website and social media channels. The survey was delivered online through a secure research data capture database. Responses were analyzed according to biological sex. Continuous variables are presented as median (25th percentile-75th percentile), and categorical variables are presented as number and proportion of participants.
resultsA total of 8919 patients reported a physician diagnosis of POTS and were included in this analysis. The majority of respondents were female (93.7%). Female and male patients experienced misdiagnosis at similar rates (76.2% vs 74.9%,
conclusionsDespite the primarily female demographic of POTS patients, female patients experience more challenges with diagnosis than male patients. Increased awareness and recognition of POTS may help to reduce the diagnostic challenges in both female and male patients, and improve treatment and management for individuals living with this debilitating disorder.
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Registered trials
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