ArticleCurrent developments in nutrition2021
Challenges for Estimating the Global Prevalence of Micronutrient Deficiencies and Related Disease Burden: A Case Study of the Global Burden of Disease Study.
Article in Current developments in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07483645 (Effectiveness and Acceptability of a Liposomal Iron Supplement With Vitamin C and Fiber), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness and Acceptability of a Liposomal Iron Supplement With Vitamin C and Fiber (LISEFEX®): Observational, Descriptive, Prospective, Longitudinal, Multicenter Study in Mexican Subjects Diagnosed With Mild to Moderate Iron Deficiency Anemia.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Biochemical assessment of the nutritional status of infants, children and adolescents in South Africa (1997-2022): a systematic review.Public health nutrition · 2024Pooled it
- The prevalence of vitamin A deficiency and its public health significance in children in low- and middle-income countries: A systematic review and modelling analysis.Journal of global health · 2023Pooled it
- Balancing Environmental Sustainability and Nutrition: Dietary Climate Impact in Relation to Micronutrient Intake and Status in a Swedish Cohort.Current developments in nutrition · 2025Article
- Consumption of Vitamin A Rich Foods and Their Primary Dietary Sources among Rural Preschoolers in the Gambella Region, Southwest Ethiopia.Ethiopian journal of health sciences · 2025Article
- Micronutrient bioavailability: concepts, influencing factors, and strategies for improvement.Frontiers in nutrition · 2025Review
- Burden of anemia in the United States from 1990 to 2019: a systematic analysis of the Global Burden of Disease Study 2019.Frontiers in public health · 2025Review
- Global estimation of dietary micronutrient inadequacies: a modelling analysis.The Lancet. Global health · 2024Article
- Comparison of Published Estimates of the National Prevalence of Iron, Vitamin A, and Zinc Deficiency and Sources of Inconsistencies.Advances in nutrition (Bethesda, Md.) · 2023Review
- The challenge of defining the global burden of iron deficiency anaemia.The Lancet. Haematology · 2023Article
- Accelerating action to reduce anemia: Review of causes and risk factors and related data needs.Annals of the New York Academy of Sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Information on the prevalence of micronutrient deficiencies is needed to determine related disease burden; underpin evidence-based advocacy; and design, deliver, and monitor safe, effective interventions. Assessing the global prevalence of deficiency requires a valid micronutrient status biomarker with an appropriate cutoff to define deficiency and relevant data from representative surveys across multiple locations and years. The Global Burden of Disease Study includes prevalence estimates for iodine, iron, zinc, and vitamin A deficiencies, for which recommended biomarkers and appropriate deficiency cutoffs exist. Because representative survey data are lacking, only retinol concentration is used to model vitamin A deficiency, and proxy indicators are used for the other micronutrients (goiter for iodine, hemoglobin for iron, and dietary food adequacy for zinc). Because of data limitations, complex statistical modeling is required to produce current estimates, relying on assumptions and proxies that likely understate the extent of micronutrient deficiencies and the consequent global health burden.
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