Evidence map›Paper›PMID 34993308›Full record

ArticleTransgender health2021

Cardiometabolic Parameters Among Transgender Adolescent Males on Testosterone Therapy and Body Mass Index-Matched Cisgender Females.

Anna Valentine, Natalie Nokoff, Andrea Bonny, Gayathri Chelvakumar, Justin Indyk, Scott Leibowitz, Leena Nahata

Open access · greenAbstract read
In one paragraph

Article in Transgender health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna ValentineDepartment of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.
Natalie NokoffDepartment of Pediatrics, Division of Endocrinology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
Andrea BonnyThe Ohio State University College of Medicine, Columbus, Ohio, USA.
Gayathri ChelvakumarThe Ohio State University College of Medicine, Columbus, Ohio, USA.
Justin IndykThe Ohio State University College of Medicine, Columbus, Ohio, USA.
Scott LeibowitzThe Ohio State University College of Medicine, Columbus, Ohio, USA.
Leena NahataThe Ohio State University College of Medicine, Columbus, Ohio, USA.
Nationwide Children's Hospital · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth (PUBERTY)K23HL151868 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI NOKOFF, NATALIE J · 2020 to 2024
$941k
NHLBI NIH HHS K23 HL151868
6 · The paper itself

Abstract

Limited data are available on changes in metabolic parameters in transgender youth on testosterone therapy in comparison with cisgender females. Data from 42 transgender males on testosterone therapy were retrospectively analyzed. Body mass index (BMI) and lipid profile changes were compared with BMI-matched females. There was a significant increase in BMI over time in the transgender males as compared with the cisgender females, and a decrease in high-density lipoprotein in the transgender males after starting testosterone therapy. Longitudinal prospective studies with cisgender controls are needed to better define effects of testosterone therapy in adolescents.

Indexed as

adolescentBMIcholesteroltestosteronetransgender

Identifiers

PMID34993308
PMCPMC8664095
OpenAlexW3113935331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.