Evidence map›Paper›PMID 34993152›Full record

ArticleFrontiers in oncology2021

Deep Learning Enables Prostate MRI Segmentation: A Large Cohort Evaluation With Inter-Rater Variability Analysis.

Yongkai Liu, Qi Miao, Chuthaporn Surawech, Haoxin Zheng, Dan Nguyen, Guang Yang, Steven S Raman, Kyunghyun Sung

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Yongkai LiuDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Qi MiaoDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Chuthaporn SurawechDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Haoxin ZhengDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Dan NguyenMedical Artificial Intelligence and Automation Laboratory, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Guang YangNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Steven S RamanDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Kyunghyun SungDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
University of California, Los Angeles · USChulalongkorn University · THFirst Hospital of China Medical University · CNImperial College London · GBThe University of Texas Southwestern Medical Center · US

Funding

Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer ClassificationR01CA248506 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUNG, KYUNG HYUN, WU, HOLDEN H · 2020 to 2024
$3.0M
Medical Research Council MC_PC_21013Medical Research Council MR/V023799/1NCI NIH HHS R01 CA248506
6 · The paper itself

Abstract

Whole-prostate gland (WPG) segmentation plays a significant role in prostate volume measurement, treatment, and biopsy planning. This study evaluated a previously developed automatic WPG segmentation, deep attentive neural network (DANN), on a large, continuous patient cohort to test its feasibility in a clinical setting. With IRB approval and HIPAA compliance, the study cohort included 3,698 3T MRI scans acquired between 2016 and 2020. In total, 335 MRI scans were used to train the model, and 3,210 and 100 were used to conduct the qualitative and quantitative evaluation of the model. In addition, the DANN-enabled prostate volume estimation was evaluated by using 50 MRI scans in comparison with manual prostate volume estimation. For qualitative evaluation, visual grading was used to evaluate the performance of WPG segmentation by two abdominal radiologists, and DANN demonstrated either acceptable or excellent performance in over 96% of the testing cohort on the WPG or each prostate sub-portion (apex, midgland, or base). Two radiologists reached a substantial agreement on WPG and midgland segmentation (

Indexed as

deep attentive neural networklarge cohort evaluationprostate segmentationqualitative evaluationquantitative evaluationvolume measurement

Identifiers

PMID34993152
PMCPMC8724207
OpenAlexW4200127817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.