ArticleFrontiers in oncology2021
Classification of Adverse Events Following Surgery in Patients With Diffuse Lower-Grade Gliomas.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Smartphone-Based Monitoring of Quality of Life and Adverse Events After Neurosurgery: Prospective Cohort Study.Journal of medical Internet research · 2026Article
- Improving quality of care for patients with high-grade glioma and their informal caregivers: Insights from focus groups with healthcare professionals.Neuro-oncology practice · 2026Article
- Adverse events in meningioma surgery classified using the therapy-disability-neurology (TDN) grading system.Journal of neuro-oncology · 2025Article
- International survey-based assessment of the reliability, validity, and interpretability of the TDN grade for neurosurgical adverse events.Scientific reports · 2025Article
- Let's talk about complications.Surgical neurology international · 2025Article
- Optimizing patient outcome in intracranial tumor surgery: a detailed prospective study of adverse events and mortality reduction strategies in neurosurgery.Acta neurochirurgica · 2024Article
- High costs, low quality of life, reduced survival, and room for improving treatment: an analysis of burden and unmet needs in glioma.Frontiers in oncology · 2024Review
- Significant perioperative parameters affecting postoperative complications within 30 days following craniotomy for primary malignant brain tumors.Perioperative medicine (London, England) · 2023Article
- Impact of in-hospital postoperative complications on quality of life up to 12 months after major abdominal surgery.The British journal of surgery · 2023Article
- Cranial meningioma with bone involvement: surgical strategies and clinical considerations.Acta neurochirurgica · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, the Therapy-Disability-Neurology (TDN) was introduced as a multidimensional reporting system to detect adverse events in neurosurgery. The aim of this study was to compare the novel TDN score with the Landriel
methodsWe screened adult patients with a surgically treated dLGG World Health Organization (WHO) grade 2 and 3 between 2010 and 2020. Up until 2017, it consists of a retrospective cohort (
resultsIn total, 231 patients were included. In 110/231 (47.6%) of the surgical procedures, a postoperative complication was registered. When comparing the TDN score to LIC grades, only a minor shift towards complications of higher order could be observed. EQ-5D 3L was reported for 45 patients. Patients with complications related to surgery had pre- to postoperative changes in EQ-5D 3L index values (
conclusionsIn patients with dLGG, TDN scores compared to the standard LIC tend to capture more adverse events of higher order. There was no clear relation between TDN severity and HRQoL. However, new-onset neurological deficit caused impairment in HRQoL. For the TDN score to better align with patient-reported outcomes, more emphasis on neurological deficit and function should be considered.
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