ArticleQuantitative imaging in medicine and surgery2022
Retinal thickness and microvascular alterations in the diagnosis of systemic lupus erythematosus: a new approach.
Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Subclinical ocular microvascular involvement in primary antiphospholipid syndrome and antiphospholipid antibody carriers.Lupus science & medicine · 2026Article
- Guidelines for visual cognitive rehabilitation of visual information processing disorders (2025).International journal of ophthalmology · 2026Article
- Guidelines for preoperative visual function and imaging examination standards in vitreoretinal surgery (2025).International journal of ophthalmology · 2025Article
- Vasculature alteration of foveal zone in systemic lupus erythematosus: a Meta-analysis.International journal of ophthalmology · 2025Article
- Retinal sublayer analysis in juvenile systemic lupus erythematosus without lupus retinopathy.Clinical rheumatology · 2024Article
- Retinal microvascular changes in patients with pancreatitis and their clinical significance.Scientific reports · 2024Article
- Retinal vessel density and choroidal flow changes in oligoarticular juvenile idiopathic arthritis with and without uveitis.Japanese journal of ophthalmology · 2024Article
- Ocular microvascular alteration in patients with myocardial infarction-a new OCTA study.Scientific reports · 2024Article
- Unveiling Ocular Manifestations in Systemic Lupus Erythematosus.Journal of clinical medicine · 2024Review
- Quantitative assessment of retinal vasculature changes in systemic lupus erythematosus using wide-field OCTA and the correlation with disease activity.Frontiers in immunology · 2024Observational
- Ocular fundus changes and association with systemic conditions in systemic lupus erythematosus.Frontiers in immunology · 2024Review
- Clinical Research of Lupus Retinopathy: Quantitative Analysis of Retinal Vessels by Optical Coherence Tomography Angiography in Patients with Systemic Lupus Erythematosus.Diagnostics (Basel, Switzerland) · 2023Article
- Involvement of the systemic microcirculation in pediatric uveitis.Pediatric rheumatology online journal · 2023Article
- Ocular microvascular alteration in Sjögren's syndrome treated with hydroxychloroquine: an OCTA clinical study.Therapeutic advances in chronic disease · 2023Article
- Understanding Ocular Findings and Manifestations of Systemic Lupus Erythematosus: Update Review of the Literature.International journal of molecular sciences · 2022Review
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the differences of retinal thickness (RT) and superficial vascular density (SVD) between patients with systemic lupus erythematosus (SLE) and healthy controls using optical coherence tomography angiography (OCTA).
methodsIndividuals with SLE (n=12; 24 eyes) and healthy controls (n=12; 24 eyes) were recruited to this study. The study protocol was in accordance with the tenets of the Declaration of Helsinki (as revised in 2013). The monocular best-corrected visual acuity (BCVA) was determined using a Snellen eye chart. Each image was segmented into 9 early treatment diabetic retinopathy study subregions, within which the macular RT and SVD were measured by OCTA. The vascular perfusion area as a percentage of the measured area was considered to be the vascular density.
resultsThe mean age of the SLE group was 33.80±9.49 years, and the mean age of the control group was 33.20±9.41 years. The mean duration of SLE was 4.33±2.67 years. The BCVA was significantly different between the SLE and control groups (0.17±0.20
conclusionsVariations in RT within the macular area may affect visual acuity. The OCTA measurement of RT may be a potential marker for diagnosis of SLE and an indicator of its inflammatory activity.
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