ArticleQuantitative imaging in medicine and surgery2022
Prognostic value of regional strain by cardiovascular magnetic resonance feature tracking in hypertrophic cardiomyopathy.
Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Prognostic value of CMR-derived myocardial strain in hypertrophic cardiomyopathy: a systematic review and meta-analysis.The international journal of cardiovascular imaging · 2026Pooled it
- Agreement Between Echocardiography and Cardiac MRI in Assessing Function, Strain, and Fibrosis in Pediatric Hypertrophic Cardiomyopathy: A Preliminary Study.Pediatric cardiology · 2026Article
- Relationships between QRS duration and left ventricular deformation in hypertrophic cardiomyopathy.Quantitative imaging in medicine and surgery · 2025Article
- Early detection of right atrial dysfunction in patients with hypertrophic cardiomyopathy using cardiac magnetic resonance feature tracking.Quantitative imaging in medicine and surgery · 2025Article
- The value of left ventricular T1 mapping and left atrial strain for distinguishing myocardial amyloidosis and hypertrophic cardiomyopathy.The international journal of cardiovascular imaging · 2025Article
- Impact of glucose metabolism on myocardial fibrosis and inflammation in hypertrophic cardiomyopathy: a cardiac MR study.Frontiers in endocrinology · 2025Article
- Right ventricular function and determining factors of dysfunction in ST-segment-elevation myocardial infarction: a cross-sectional study with cardiac magnetic resonance imaging (MRI).Quantitative imaging in medicine and surgery · 2024Article
- Left atrial and left ventricular strain in feature-tracking cardiac magnetic resonance for predicting patients at high risk of sudden cardiac death in hypertrophic cardiomyopathy.Quantitative imaging in medicine and surgery · 2024Article
- Cardiac magnetic resonance analysis of left atrium function in patients with pre-apical hypertrophic cardiomyopathy.Quantitative imaging in medicine and surgery · 2024Article
- Morphology of hypertrophied basal septum contributes to left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy: a retrospective case-control study.Quantitative imaging in medicine and surgery · 2023Article
- Cardiac cine with compressed sensing real-time imaging and retrospective motion correction for free-breathing assessment of left ventricular function and strain in clinical practice.Quantitative imaging in medicine and surgery · 2023Article
- Value of cardiac magnetic resonance feature tracking technology in the differential diagnosis of isolated left ventricular noncompaction and dilated cardiomyopathy.Quantitative imaging in medicine and surgery · 2023Article
- Cardiac magnetic resonance-derived tissue tracking strain in patients with hypertrophic cardiomyopathy.Quantitative imaging in medicine and surgery · 2023Article
- Cardiac Multimodality Imaging in Hypertrophic Cardiomyopathy: What to Look for and When to Image.Current cardiology reviews · 2023Review
- The predictive value of cardiac MRI strain parameters in hypertrophic cardiomyopathy patients with preserved left ventricular ejection fraction and a low fibrosis burden: a retrospective cohort study.Frontiers in cardiovascular medicine · 2023Article
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8 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have demonstrated the performance of regional strain by cardiovascular magnetic resonance (CMR) feature tracking in hypertrophic cardiomyopathy (HCM) patients, and the prognostic value of segmental strain remains unknown. This study aimed to explore the prognostic implications of strain parameters generated by CMR feature tracking analysis in HCM patients.
methodsIn total, 104 clinically diagnosed HCM patients and 30 healthy volunteers were enrolled in this study, and all patients underwent a standard CMR examination. Global and regional strain was computed by short axis, 2-, 3-, and 4-chamber view cine MR imaging using specialized software. Cardiac structure, function, and myocardial strain were compared between the control group and HCM patients, and the event and event-free groups. Univariate and multivariate Cox regression analyses were performed to evaluate the correlations between clinical and CMR parameters and poor prognosis.
resultsDuring the follow-up time, 8 patients reached the primary end points and 14 patients reached secondary end points. Regional radial strain of hypertrophic segments (RRS) and regional circumferential strain of hypertrophic segments (RCS) were worse in HCM patients with primary and secondary end points. In univariate Cox regression analysis of RRS, RCS were associated with primary and secondary end points. Regional radial strain of hypertrophic segments [hazard ratio (HR) 1.64, 95% confidence interval (CI): 1.13-2.38] and RCS (HR 2.35, 95% CI: 1.20-4.59) were independent predictors of primary end points, and RRS (HR 1.71, 95% CI: 1.09-2.66) and RCS (HR 2.63, 95% CI: 1.20-5.75) remained independent predictors of secondary end points in multivariate analysis. Kaplan-Meier survival curves indicated patients with RRS <10.0% and RCS ≥-8.5% had a higher rate of primary end points, and patients with RRS <17.9% and RCS ≥-12.1% experienced a higher rate of secondary end points.
conclusionsIn HCM patients, RRS and RCS were associated with primary and secondary end points and remained independent predictors in multivariate analysis. Impaired regional strain may potentially predict poor prognosis in HCM patients. KEYWORDS: Prognosis; hypertrophic cardiomyopathy (HCM); cardiovascular magnetic resonance (CMR); regional strain.
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