ArticleQuantitative imaging in medicine and surgery2022
Comparison of contrast-enhanced T1-weighted imaging using DANTE-SPACE, PETRA, and MPRAGE: a clinical evaluation of brain tumors at 3 Tesla.
Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 16 citations in OpenAlex.
- Improving small brain metastasis detection with composite and augmented TQuantitative imaging in medicine and surgery · 2026Article
- Oncological value of MRI in brain metastasis: exploring the potential of combining post-contrast T1 TSE (SPACE) and T1 GRE (MPRAGE) for stereotactic radiosurgery planning and surveillance.Journal of neuro-oncology · 2025Article
- Prospective comparison of brain tumor detection and characterization using post-contrast Dixon uT1RESS and MPRAGE at 3 Tesla.European journal of radiology · 2025Article
- 3 Tesla stack-of-stars echo unbalanced T1 relaxation-enhanced steady-state MRI for brain tumor imaging: post-contrast comparison with MPRAGE.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Observational
- Radiomics-Based Differentiation of Glioblastoma and Metastatic Disease: Impact of Different T1-Contrast-Enhanced Sequences on Radiomics Features and Model Performance.AJNR. American journal of neuroradiology · 2025Article
- An evaluation of image-based and statistical techniques for harmonizing brain volume measurements.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Diagnostics and Screening in Breast Cancer with Brain and Leptomeningeal Metastasis: A Review of the Literature.Cancers · 2024Review
- Exploring the Impact of 3D Fast Spin Echo and Inversion Recovery Gradient Echo Sequences Magnetic Resonance Imaging Acquisition on Automated Brain Tumor Segmentation.Mayo Clinic proceedings. Digital health · 2024Article
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9 authors at 6 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to compare the performance of three contrast-enhanced T1-weighted three-dimensional (3D) magnetic resonance (MR) sequences to detect brain tumors at 3 Tesla. The three sequences were: (I) delay alternating with nutation for tailored excitation sampling perfection with application-optimized contrasts using different flip angle evolution (DANTE-SPACE), (II) pointwise encoding time reduction with radial acquisition (PETRA), and (III) magnetization-prepared rapid acquisition with gradient echo (MPRAGE).
methodsThis study involved 77 consecutive patients, including 34 patients with known primary brain tumors and 43 patients suspected of intracranial metastases. All patients underwent each of the three sequences with comparable spatial resolution and acquisition time post-injection. Signal-to-noise ratios (SNRs) for gray matter (GM) and white matter (WM), contrast-to-noise ratios (CNRs) for lesion/GM, lesion/WM, and GM/WM were quantitatively compared. Two radiologists determined the total number of enhancing lesions by consensus. Intraclass correlation coefficients (ICCs) between the two radiologists for metastases presence, qualitative ratings for image quality, and acoustic noise level of each sequence were assessed.
resultsAmong the three sequences, SNRs and CNRs between lesions and surrounding parenchyma were highest using DANTE-SPACE, but CNR
conclusionsPETRA achieves comparable detection of brain tumors with MPRAGE and is preferred for depicting osseous metastases and meningeal enhancement. DANTE-SPACE with blood vessel suppression showed improved detection of cerebral metastases compared with MPRAGE and PETRA, which could be helpful for the differential diagnosis of tumors.
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