Evidence map›Paper›PMID 34993064›Full record

ArticleQuantitative imaging in medicine and surgery2022

The quantitative evaluation of contrast-enhanced ultrasound in the differentiation of small renal cell carcinoma subtypes and angiomyolipoma.

Hui Liu, Hongli Cao, Lin Chen, Liang Fang, Yingchun Liu, Jia Zhan, Xuehong Diao, Yue Chen

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Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

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  15. Contrast-Enhanced Ultrasound Features of Adult Xp11.2 Translocation Renal Cell Carcinoma: Differential Diagnosis With Three Main Renal Cell Carcinoma Subtypes.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hui Liu *Department of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Hongli Cao *Department of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Lin ChenDepartment of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Liang FangDepartment of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Yingchun LiuDepartment of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Jia ZhanDepartment of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Xuehong DiaoDepartment of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Yue ChenDepartment of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuadong Hospital · CNYangPu Geriatric Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContrast-enhanced ultrasound (CEUS) has been widely used for renal lesion diagnosis and differential diagnosis. However, qualitative analysis of CEUS is subject to examinations with low reproducibility. This study aims to investigate the diagnostic value of CEUS quantitative parameters in differentiating small renal cell carcinoma (RCC) subtypes and angiomyolipoma (AML).

methodsA retrospective analysis was performed on 97 cases of a small renal mass undergoing a CEUS before a radical or partial nephrectomy procedure. A region of interest (ROI) was placed in the tumor's maximum enhanced region (ROI

resultsIn RCC and clear cell renal cell carcinoma (ccRCC), the peak intensity (PI), slope (SL), area under the curve (AUC), area under the wash-in curve (AWI), area under the wash-out curve (AWO), time to peak intensity (TTP) and the mean transit time (MTT) were statistically significant between ROI

conclusionsCEUS quantitative parameters have value in differentiating small RCC from AML and distinguishing ccRCC from pRCC and chRCC.

Indexed as

angiomyolipoma (AML)contrast-enhanced ultrasound (CEUS)quantitative analysisRenal cell carcinoma (RCC)

Identifiers

PMID34993064
PMCPMC8666748
OpenAlexW3183173649

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.