Evidence map›Paper›PMID 34992969›Full record

ArticleNeurology. Clinical practice2021

Improved Cognitive Function in the Tromsø Study in Norway From 2001 to 2016.

Bente Johnsen, Bjørn Heine Strand, Ieva Martinaityte, Ellisiv B Mathiesen, Henrik Schirmer

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bente JohnsenDepartment of Clinical Medicine (BJ, IM, EBM, HS), UiT The Arctic University of Norway; Department of Medicine (BJ, IM), University Hospital of North Norway, Tromsø; Norwegian Institute of Public Health (BHS), Oslo; Department of Neurology (EBM), University Hospital of North Norway, Tromsø; Department of Cardiology (HS), Akershus University Hospital, Lørenskog; and Institute of Clinical Medicine (HS), University of Oslo, Norway.
Bjørn Heine StrandDepartment of Clinical Medicine (BJ, IM, EBM, HS), UiT The Arctic University of Norway; Department of Medicine (BJ, IM), University Hospital of North Norway, Tromsø; Norwegian Institute of Public Health (BHS), Oslo; Department of Neurology (EBM), University Hospital of North Norway, Tromsø; Department of Cardiology (HS), Akershus University Hospital, Lørenskog; and Institute of Clinical Medicine (HS), University of Oslo, Norway.
Ieva MartinaityteDepartment of Clinical Medicine (BJ, IM, EBM, HS), UiT The Arctic University of Norway; Department of Medicine (BJ, IM), University Hospital of North Norway, Tromsø; Norwegian Institute of Public Health (BHS), Oslo; Department of Neurology (EBM), University Hospital of North Norway, Tromsø; Department of Cardiology (HS), Akershus University Hospital, Lørenskog; and Institute of Clinical Medicine (HS), University of Oslo, Norway.
Ellisiv B MathiesenDepartment of Clinical Medicine (BJ, IM, EBM, HS), UiT The Arctic University of Norway; Department of Medicine (BJ, IM), University Hospital of North Norway, Tromsø; Norwegian Institute of Public Health (BHS), Oslo; Department of Neurology (EBM), University Hospital of North Norway, Tromsø; Department of Cardiology (HS), Akershus University Hospital, Lørenskog; and Institute of Clinical Medicine (HS), University of Oslo, Norway.
Henrik SchirmerDepartment of Clinical Medicine (BJ, IM, EBM, HS), UiT The Arctic University of Norway; Department of Medicine (BJ, IM), University Hospital of North Norway, Tromsø; Norwegian Institute of Public Health (BHS), Oslo; Department of Neurology (EBM), University Hospital of North Norway, Tromsø; Department of Cardiology (HS), Akershus University Hospital, Lørenskog; and Institute of Clinical Medicine (HS), University of Oslo, Norway.
Norwegian Institute of Public Health · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesPhysical capacity and cardiovascular risk profiles seem to be improving in the population. Cognition has been improving due to a birth cohort effect, but evidence is conflicting on whether this improvement remains in the latest decades and what is causing the changes in our population older than 60 years. We aimed to investigate birth cohort differences in cognition.

methodsThe study comprised 9,514 participants from the Tromsø Study, an ongoing longitudinal cohort study. Participants were aged 60-87 years, born between 1914 and 1956. They did 4 cognitive tests in 3 waves during 2001-2016. Linear regression was applied and adjusted for age, education, blood pressure, smoking, hypercholesterolemia, stroke, heart attack, depression, diabetes, physical activity, alcohol use, BMI, and height.

resultsCognitive test scores were better in later-born birth cohorts for all age groups, and in both sexes, compared with earlier-born cohorts. Increased education, physical activity, alcohol intake, decreasing smoking prevalence, and increasing height were associated with one-third of this improvement across birth cohorts in women and one-half of the improvement in men. DISCUSSION: Cognitive results were better in more recent-born birth cohorts compared with earlier born, assessed at the same age. The improvement was present in all cognitive domains, suggesting an overall improvement in cognitive performance. The 80-year-olds assessed in 2015-2016 performed like 60-year-olds assessed in 2001. The improved scores were associated with increased education level, increase in modest drinking frequency, increased physical activity, and, for men, smoking cessation and increased height.

Identifiers

PMID34992969
PMCPMC8723922
OpenAlexW3173609342

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.