ArticleNeurology. Clinical practice2021
Pain Phenotypes in Adults Living With Cerebral Palsy.
Article in Neurology. Clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pain in adults with cerebral palsy: A systematic review.Developmental medicine and child neurology · 2025Pooled it
- Evidence-Based Classification, Assessment, and Management of Pain in Children with Cerebral Palsy: A Structured Review.Healthcare (Basel, Switzerland) · 2025Review
- Cerebral Palsy Link to Sensorimotor System, Cognition, Emotion and Nociplastic Pain.Children (Basel, Switzerland) · 2025Review
- Medication and Therapy Profiles for Pain and Symptom Management Among Adults With Cerebral Palsy.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Post-operative pain and success rate after pulpotomy with symptomatic irreversible pulpitis: A review.Bioinformation · 2025Article
- A second dimension of somatosensory system injury? Thalamic volume loss and neuropathic pain in adults with cerebral palsy and periventricular white matter injury.Annals of the Child Neurology Society · 2023Article
- Population- and individual-level trajectories of opioid prescription patterns among adults with cerebral palsy: a retrospective cohort study.International journal of clinical pharmacy · 2023Article
- Impairments and comorbidities in adults with cerebral palsy and spina bifida: a meta-analysis.Frontiers in neurology · 2023Review
- Article
- Navigating the Pathway to Care in Adults With Cerebral Palsy.Frontiers in neurology · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesTo identify pain phenotypes among adults living with cerebral palsy (CP) and compare phenotypes of pain intensity, anxiety and depressive symptoms, and self-reported perceived stress.
methodsSeventy-one adults with CP presented to the University of Michigan (mean age = 39.3 ± 16.2; 43 women, 28 men). The median of 6 on the American College of Rheumatology fibromyalgia survey was used to classify patients for nociplastic pain centralization. The painDETECT Score was used to classify patients for neuropathic pain. These measures were then used to cross-classify each patient into 1 of 4 possible pain categories: neuropathic, nociplastic, mixed neuropathic/noclipastic, or nociceptive pain (-neuropathic/-nociplastic pain).
resultsTwenty-eight adults with CP (39.4%) were classified as nociceptive, 24 (33.8%) as nociplastic, 8 (11.3%) as neuropathic, and 11 (15.5%) as mixed neuropathic/nociplastic. Subgroups differed significantly on average scores on the Brief Pain Inventory pain intensity scale, the Perceived Stress Scale, and on the Patient-Reported Outcomes Measurement Information System measures of anxiety and depression; the nociceptive pain subgroup reported lower pain and emotional distress compared with the other groups. DISCUSSION: Findings suggest that type of pain is variable among adults with CP and may arise through multiple mechanisms.
Identifiers
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Registered trials
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