Evidence map›Paper›PMID 34992967›Full record

ArticleNeurology. Clinical practice2021

Aspiration Pneumonia in Adults Hospitalized With Stroke at a Large Academic Hospital in Zambia.

Morgan L Prust, Aparna Nutakki, Gloria Habanyama, Lorraine Chishimba, Mashina Chomba, Moses Mataa, Kunda Yumbe, Stanley Zimba, Rebecca F Gottesman, Mona N Bahouth and 1 more

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In one paragraph

Article in Neurology. Clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  6. A simple nomogram for predicting aspiration associated with dysphagia in hospitalized patients after stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Morgan L PrustDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Aparna NutakkiDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-8270-6140
Gloria HabanyamaDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Lorraine ChishimbaDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Mashina ChombaDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Moses MataaDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Kunda YumbeDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Stanley ZimbaDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Rebecca F GottesmanDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Mona N BahouthDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Deanna R SaylorDepartment of Neurology (MLP), Division of Neurocritical Care, Columbia University Medical Center, New York, NY; Rush University Medical College (AN), Chicago, IL; Department of Medicine (GH, LC, MC, MM, DRS), University of Zambia School of Medicine, Lusaka; Department of Medicine (KY, SZ, DRS), University Teaching Hospital, University of Zambia, Lusaka; and Department of Neurology (RFG, MNB, DRS), Johns Hopkins University School of Medicine, Baltimore, MD.
Rush University Medical Center · US

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
FIC NIH HHS D43 TW009340
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPreventing complications of stroke such as poststroke aspiration pneumonia (PSAP) may improve stroke outcomes in resource-limited settings. We investigated the incidence and associated mortality of PSAP in Zambia.

methodsWe conducted a prospective cohort study of adults with stroke at University Teaching Hospital (Lusaka, Zambia) between December 2019 and March 2020. NIH Stroke Scale, Glasgow Coma Scale, and Modified Rankin Scale scores and 9 indicators of possible PSAP were collected serially over each participant's admission. PSAP was defined as ≥4 indicators present, and possible PSAP as 2%-3% present. T tests and χ

resultsWe enrolled 125 participants. Mean age was 60 ± 16 years, 61% were female, 55% of strokes were ischemic, and the baseline NIH Stroke Scale score was 19.7 ± 8.7. Thirty-eight (30%) had PSAP, and 32 (26%) had possible PSAP. PSAP was associated with older age and more adverse stroke severity scores. Fifty-nine percent of participants with PSAP died compared with 39% with possible PSAP and 8% with no PSAP. PSAP status independently predicted inpatient mortality after controlling for age, sex, and initial stroke severity. Swallow screening was not performed for any participant. DISCUSSION: PSAP is common and life threatening in Zambia, especially among older participants with severe stroke presentations. PSAP was associated with significantly increased mortality independent of initial stroke severity, suggesting that interventions to mitigate PSAP may improve stroke outcomes in Zambia and other resource-limited settings.

Identifiers

PMID34992967
PMCPMC8723975
OpenAlexW3173816479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.