Evidence map›Paper›PMID 34992940›Full record

ReviewSurgical neurology international2021

The efficacy of cystoperitoneal shunting for the surgical management of intracranial arachnoid cysts in the elderly: A systematic review of the literature.

Joseph Merola, Susruta Manivannan, Setthasorn Ooi, Wen Li Chia, Milan Makwana, Jozsef Lang, Paul Leach, Malik J Zaben

Open access · hybridAbstract readReview
In one paragraph

Review in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Surgical management of complicated arachnoid cysts: A case series.International journal of surgery case reports · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ruptured Sylvian arachnoid cysts: an update on a real problem.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Joseph MerolaDepartment of Neurosciences, University Hospital of Wales, Cardiff, United Kingdom.
Susruta ManivannanDepartment of Neurosurgery, Southampton General Hospital, Southampton General Hospital, Southampton, United Kingdom.
Setthasorn OoiInstitute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, University Hospital of Wales, United Kingdom.
Wen Li ChiaInstitute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, University Hospital of Wales, United Kingdom.
Milan MakwanaDepartment of Neurosciences, University Hospital of Wales, Cardiff, United Kingdom.
Jozsef LangDepartment of Neurosciences, University Hospital of Wales, Cardiff, United Kingdom.
Paul LeachDepartment of Neurosciences, University Hospital of Wales, Cardiff, United Kingdom.
Malik J ZabenDepartment of Neurosurgery, Cardiff and Vale University Health Board, Cardiff, United Kingdom.
University Hospital of Wales · GBCardiff and Vale University Health Board · GBSouthampton General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntracranial arachnoid cysts (AC) are benign, cerebrospinal fluid filled spaces within the arachnoid layer of the meninges. Neurosurgical intervention in children and young adults has been extensively studied, but the optimal strategy in the elderly remains unclear. Therefore, we performed a single center retrospective study combined with a systematic review of the literature to compare cystoperitoneal (CP) shunting with other surgical approaches in the elderly cohort.

methodsRetrospective neurosurgical database search between January 2005 and December 2018, and systematic review of the literature using PRISMA guidelines were performed. Inclusion criteria: Age 60 years or older, radiological diagnosis of intracranial AC, neurosurgical intervention, and neuroradiological (NOG score)/clinical outcome (COG score). Data from both sources were pooled and statistically analyzed.

resultsOur literature search yielded 12 studies (34 patients), which were pooled with our institutional data (13 patients). CP shunts (7 patients; 15%), cyst fenestration (28 patients; 60%) and cyst marsupialisation/resection (10 patients; 21%) were the commonest approaches. Average duration of follow-up was 23.6, 26.9, and 9.5 months for each approach, respectively. There was no statistically significant association between choice of surgical intervention and NOG score (

conclusionCP shunting is a safe and effective surgical treatment strategy for ACs in the elderly. It has similar clinical and radiological outcomes but superior risk profile when compared with other approaches. We advocate CP shunting as first line neurosurgical intervention for the management of intracranial ACs in the elderly.

Indexed as

Cystoperitoneal shuntEndoscopic fenestrationIntracranial arachnoid cystsMarsupialisation

Identifiers

PMID34992940
PMCPMC8720472
OpenAlexW3215683998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.