Evidence map›Paper›PMID 34992914›Full record

ReviewSurgical neurology international2021

Should the direct aspiration first pass technique be advocated over the stent-retriever technique for acute ischemic stroke? A systematic review and meta-analysis of 7692 patients.

Ahmed Negida, Hazem S Ghaith, Mohamed Diaa Gabra, Mohamed Abdelalem Aziz, Mohamed Elfil, Haider Al-Shami, Eshak I Bahbah, Ulrick Sidney Kanmounye, Ignatius Esene, Ahmed M Raslan

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Repeated mechanical thrombectomy for recurrent large vessel occlusion: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Ahmed NegidaFaculty of Medicine, Zagazig University, Zagazig University, Zagazig, Sharkia, Egypt.
Hazem S GhaithFaculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohamed Diaa GabraFaculty of Medicine, South Valley University, Qena, Egypt.
Mohamed Abdelalem AzizOmar Shahin Mental Hospital, Cairo, Egypt.
Mohamed ElfilDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, Egypt.
Haider Al-ShamiDepartment of Neurosurgery, National Bank Hospital, Cairo, Egypt.
Eshak I BahbahFaculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Ulrick Sidney KanmounyeDepartment of Research, Association of Future African Neurosurgeons, Yaounde, Cameroon, Africa.
Ignatius EseneNeurosurgery Division, Faculty of Health Sciences, University of Bamenda, Bambili, Cameroon, Africa.
Ahmed M RaslanDepartment of Neurological Surgery, Oregon Health and Science University, Portland, Oregon, United States.
Al-Azhar University · EGNational Water Research Center · EGNeurological Surgery · USSouth Valley University · EGUniversity of Bamenda · CMUniversity of Nebraska Medical Center · USZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present meta-analysis aimed to synthesize evidence from all published studies with head-to-head data on the outcomes of a direct aspiration first pass technique (ADAPT) and the stent-retriever (SR) in acute ischemic stroke (AIS) patients.

methodsWe searched PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials from inception to March 2021 for relevant clinical trials and observational studies. Eligible studies were identified, and all relevant outcomes were pooled in the meta-analysis random-effects model of DerSimonian-Laird.

resultsThirty studies were included in the meta-analysis with a total of 7868 patients. Compared with the SR, the ADAPT provides slightly higher rates of successful recanalization (RR 1.06, 95% CI [1.02 to 1.10]) and complete recanalization (RR 1.20, 95% CI [1.01 to 1.43]) but with more need for rescue therapy (RR 1.81, 95% CI [1.29 to 2.54]). There were no significant differences between the two techniques in terms of mortality at discharge, mortality at 90 days, change in the National Institutes of Health Stroke Scale score, the favorable outcome (modified Rankin scale (mRS) of 0-2), time to the groin puncture, or frequency of complications as intracerebral hemorrhage (ICH), symptomatic intracranial hemorrhage (sICH), embolus in a new territory (ENT), hemorrhagic infarction, parenchymal hematoma, subarachnoid hemorrhage, or procedural complications (all

conclusionCurrent evidence supports the use of the ADAPT technique to achieve successful and complete recanalization while considering the higher need for rescue therapy in some patients.

Indexed as

A direct aspiration first pass techniqueDirect aspiration first pass techniqueEndovascular therapyIschemic strokeMeta-analysisStent retrieverThrombectomy

Identifiers

PMID34992914
PMCPMC8720438
OpenAlexW4200102642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.