Evidence map›Paper›PMID 34992898›Full record

ArticleSurgical neurology international2021

Brain paracoccidioidomycosis in an immunosuppressed patient with systemic lupus erythematosus.

Carolina Kamer, Barbara Janke Pretto, Carlos Rafael Livramento, Rafael Carlos da Silva

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus.Clinical, cosmetic and investigational dermatology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carolina KamerDepartment of Internal Medicine, School of Medicine, Centro Universitário para o Desenvolvimento do Alto Vale do Itajaí, Rio do Sul, Santa Catarina, Brazil.
Barbara Janke PrettoDepartment of Rheumatology, Rheumatology and Immunotherapy Center of Alto Vale, Rio do Sul, Santa Catarina, Brazil.
Carlos Rafael LivramentoDepartment of Internal Medicine, School of Medicine, Centro Universitário para o Desenvolvimento do Alto Vale do Itajaí, Rio do Sul, Santa Catarina, Brazil.
Rafael Carlos da SilvaGraduate Medical Education, Piedmont Athens Regional Medical Center, Athens, Georgia, United States.
Universidade para o Desenvolvimento do Alto Vale do Itajaí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrain paracoccidioidomycosis (PCM) or neuroparacoccidioidomycosis (NPCM) is a fungal infection of the central nervous system (CNS) caused by CASE DESCRIPTION: The aim of this case report is to present a 37-year-old female with diagnosis of SLE who presented with progressive and persistent headache in the past 4 months accompanied by the right arm weakness with general and neurologic examination unremarkable. The computerized tomography of the head showed left extra-axial parietooccipital focal hypoattenuation with adjacent bone erosion. The brain magnetic resonance imaging reported left parietooccipital subdural collection associated with focal leptomeningeal thickening with restriction to diffusion and peripheral contrast enhancement. The patient underwent a left craniotomy and dura mater biopsy showed noncaseous granulomatosis with multinucleated giant cells with rounded birefringent structures positive for silver stain, consistent with PCM. Management with itraconazole 200 mg daily was started with a total of 12 months of treatment, with patient presenting resolution of headache and right arm weakness.

conclusionThe diagnosis of NPCM is challenging and a high degree of suspicious should be considered in patients with persistent headache and immunosuppression.

Indexed as

Central nervous systemNeglected diseasesNeuroparacoccidioidomycosisParacoccidioidesParacoccidioidomycosis

Identifiers

PMID34992898
PMCPMC8720419
OpenAlexW3217482157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.