Evidence map›Paper›PMID 34992882›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2021

Re-irradiation after stereotactic body radiotherapy for spine metastases from hepatocellular carcinoma: a case report.

Sitaraman BalajiSubramanian, Krishnamoorthy Sathiya, Karunakaran Balaji, Moorthi Thirunavukarasu, Surparaju Phanikiran, Mohamed Rela

Registry-linked trialOpen access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07772206 (The SMART Trial), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07772206 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The SMART Trial: A Randomised Feasibility Study Comparing Single Fraction and Multifraction Arc-Based Radiotherapy for Painful Bone Metastases

TypeinterventionalSponsorOman Ministry of HealthRan2026 to 2027Enrolled70ConditionsBone Metastases of a Malignant Tumor, Cancer PainArmsSingle-Fraction Radiotherapy (8Gy x 1#), Multifraction Radiotherapy (20 Gy in 5 #)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sitaraman BalajiSubramanianDepartment of Radiation Oncology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Krishnamoorthy SathiyaDepartment of Radiation Oncology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Karunakaran BalajiDepartment of Radiation Oncology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Moorthi ThirunavukarasuDepartment of Radiation Oncology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Surparaju PhanikiranDepartment of Spine Surgery, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Mohamed RelaInstitute of Liver Disease and Transplantation, Dr Rela Institute and Medical Centre, Chennai, Tamil Nadu, India.
Gleneagles Hospital · SGTamil Nadu Dr. M.G.R. Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern radiotherapy machines with refinements in planning software and image-guidance apparatuses have made stereotactic body radiotherapy (SBRT) more widely available as an effective tool in the management of spine metastases. In conventional palliative radiotherapy, the aim has traditionally been pain relief and short-term local control. In contrast, SBRT aims to deliver an ablative dose to enhance local control, with a smaller number of fractions while sparing the organs at risk (OAR), especially the spinal cord. Recently, trials have asserted the role of spine SBRT as an effective modality for durable local control, in addition to achieving pain relief. The quality of evidence for spine SBRT data is maturing, while prospective published trials on re-irradiation SBRT in spine remain sparse. The purpose of the present case report is to share the challenges faced while salvaging a dorsal spine metastasis and ablating a new right adrenal metastatic lesion in proximity of the transplanted liver.

Indexed as

hepatocellular carcinomaoligometastasesre-irradiationSBRTspine metastases

Identifiers

PMID34992882
PMCPMC8726434
OpenAlexW3195339568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.