Evidence map›Paper›PMID 34992738›Full record

SynthesisEuropean journal of psychotraumatology2021

Pharmacological therapy for post-traumatic stress disorder: a systematic review and meta-analysis of monotherapy, augmentation and head-to-head approaches.

Mathew D Hoskins, Jack Bridges, Robert Sinnerton, Anna Nakamura, Jack F G Underwood, Alan Slater, Matthew R D Lee, Liam Clarke, Catrin Lewis, Neil P Roberts and 1 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of psychotraumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 12 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 12 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. Magnitude of response in treatment and control groups within psychedelic trials for psychiatric disorders: A meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mathew D HoskinsDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Jack BridgesDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Robert SinnertonDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Anna NakamuraDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Jack F G UnderwoodDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Alan SlaterDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Matthew R D LeeDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Liam ClarkeDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Catrin LewisDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.
Neil P RobertsDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.ORCID 0000-0002-6277-0102
Jonathan I BissonDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK.ORCID 0000-0001-5170-1243
Cardiff University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenergic alpha-1 Receptor AntagonistsAntipsychotic AgentsDrug SynergismDrug Therapy, CombinationHumansSelective Serotonin Reuptake InhibitorsStress Disorders, Post-TraumaticAdrenergic alpha-1 Receptor AntagonistsAntipsychotic AgentsSelective Serotonin Reuptake Inhibitorsmedicationmeta-analysispharmacological therapyPTSDsystematic review

Identifiers

PMID34992738
PMCPMC8725683
OpenAlexW3123716570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.