Evidence map›Paper›PMID 34992716›Full record

ArticleOxidative medicine and cellular longevity2021

Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene.

Martina La Spina, Michele Azzolini, Andrea Salmaso, Sofia Parrasia, Eva Galletta, Marco Schiavone, Martina Chrisam, Andrea Mattarei, Giulietta Di Benedetto, Andrea Ballabio and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Martina La SpinaDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-4478-2599
Michele AzzoliniDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-0619-3523
Andrea SalmasoDepartment of Biomedical Sciences, University of Padova, Padova, Italy.
Sofia ParrasiaDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0001-7106-6451
Eva GallettaDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0001-9060-5027
Marco SchiavoneDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-8566-5559
Martina ChrisamDepartment of Molecular Medicine, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-5328-1737
Andrea MattareiDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-2023-0749
Giulietta Di BenedettoCNR Neuroscience Institute, Padova, Italy.ORCID https://orcid.org/0000-0002-1489-3896
Andrea BallabioTelethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.ORCID https://orcid.org/0000-0003-1381-4604
Natascia TisoDepartment of Biology, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-5444-9853
Mario ZorattiDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0001-8284-2524
Lucia BiasuttoDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-7638-6865
University of Padua · ITBaylor College of Medicine · USNeuroscience Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pterostilbene (Pt) is a potentially beneficial plant phenol. In contrast to many other natural compounds (including the more celebrated resveratrol), Pt concentrations producing significant effects

Indexed as

AnimalsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDisease Models, AnimalHeLa CellsHumansMiceStilbenesTranscription FactorsZebrafishBasic Helix-Loop-Helix Leucine Zipper Transcription FactorspterostilbeneStilbenesTFEB protein, humanTranscription Factors

Identifiers

PMID34992716
PMCPMC8727145
OpenAlexW4200011682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.