Evidence map›Paper›PMID 34992631›Full record

ArticleFrontiers in genetics2021

Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies.

Nicole D Armstrong, Vinodh Srinivasasainagendra, Amit Patki, Rikki M Tanner, Bertha A Hidalgo, Hemant K Tiwari, Nita A Limdi, Ethan M Lange, Leslie A Lange, Donna K Arnett and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Integration of genetic risk, cardiometabolic diseases, and cognitive impairment among African American adults.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Epigenetics as a target to mitigate excess stroke risk in people of African ancestry: A scoping review.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Genes, environment, and African ancestry in cardiometabolic disorders.Trends in endocrinology and metabolism: TEM · 2023
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nicole D ArmstrongDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Vinodh SrinivasasainagendraDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States.
Amit PatkiDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States.
Rikki M TannerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Bertha A HidalgoDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Hemant K TiwariDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States.
Nita A LimdiDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, United States.
Ethan M LangeDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Leslie A LangeDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Donna K ArnettCollege of Public Health, University of Kentucky, Lexington, KY, United States.
Marguerite R IrvinDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
University of Alabama at Birmingham · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Kentucky · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
Predictors of hemorrhage among patients on direct acting oral anticoagulantsR01HL092173 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIMDI, NITA A · 2008 to 2023
$10.4M
Cardiorenal Genomics for Risk Prediction in African Descent PopulationsR35HL155466 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Marguerite R Irvin · 2021 to 2026
$5.1M
Genomic Background of Blood Pressure Response to Thiazide Diuretic in African AmericansR01HL123782 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI IRVIN, MARGUERITE R · 2016 to 2020
$3.7M
Genetic underpinnings of cardiorenal risk in Africans and African AmericansR01HL136666 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI IRVIN, MARGUERITE R, LANGE, LESLIE A · 2017 to 2020
$2.6M
NHLBI NIH HHS R01 HL092173NHLBI NIH HHS R01 HL123782NHLBI NIH HHS R01 HL136666NHLBI NIH HHS R35 HL155466NIDDK NIH HHS P30 DK079626NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antihypertensivesdisparitiesgenome wide association studieshypertensionincident strokepolygenic risk score

Identifiers

PMID34992631
PMCPMC8724550
OpenAlexW4200195780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.