Evidence map›Paper›PMID 34992606›Full record

Observational studyFrontiers in immunology2021

New Evidence of Gut Microbiota Involvement in the Neuropathogenesis of Bipolar Depression by

Jianbo Lai, Peifen Zhang, Jiajun Jiang, Tingting Mou, Yifan Li, Caixi Xi, Lingling Wu, Xingle Gao, Danhua Zhang, Yiqing Chen and 6 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Jianbo LaiDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Peifen ZhangDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jiajun JiangDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Tingting MouDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yifan LiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Caixi XiDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lingling WuDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xingle GaoDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Danhua ZhangDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yiqing ChenDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huimin HuangInstitute of Psychiatry, Wenzhou Medical University, Wenzhou, China.
Huijuan LiKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Xin CaiKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Ming LiKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Peng ZhengDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shaohua HuDepartment of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
First Affiliated Hospital Zhejiang University · CNChinese Institute for Brain Research · CNChongqing Medical University · CNKunming Institute of Zoology · CNChinese Academy of Sciences · CNWenzhou Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetratricopeptide repeat and ankyrin repeat containing 1 (

Indexed as

AdolescentAdultAnimalsBipolar DisorderBrain-Gut AxisCase-Control StudiesCell LineCytokinesDepressionDisease Models, AnimalFecal Microbiota TransplantationFemaleGastrointestinal MicrobiomeHealthy VolunteersHippocampusHumansCytokinesLipopolysaccharidesTRANK1 protein, humanbipolar disorderfecal microbiota transplantationgut microbiotaneuroinflammationTRANK1

Identifiers

PMID34992606
PMCPMC8724122
OpenAlexW4200356594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.