ArticleInternational journal of general medicine2021
Influence of the Interaction Between Depressive Symptoms and Sleep Disorders on Cardiovascular Diseases Occurrence.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 13 citations in OpenAlex.
- Benefits and risks of sleep medication in individuals with hypertension and sleep disturbance: evidence from a large population-based study.BMC cardiovascular disorders · 2025Article
- Interaction effects between sleep-related disorders and depression on hypertension among adults: a cross-sectional study.BMC psychiatry · 2024Article
- Depressive Symptoms and Mortality Among US Adults.JAMA network open · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDepressive symptoms and sleep disorders were independent risk factors for cardiovascular diseases (CVD). However, few studies have examined the combined effects of depressive symptoms and sleep disorders on CVD. We aimed to evaluate the association between depressive symptoms, sleep disorders and CVD occurrence.
methodsData on 30,398 participants were extracted from the National Health and Nutritional Examination Survey (NHANES) database (2005-2018). Univariate and multivariate analyses were used for assessing the association of depressive symptoms, sleep disorders, and CVD occurrence. Three indexes, including the relative excess risk of interaction (RERI), attributable proportion of interaction (API), and synergy index (SI), were used to analyze the interaction.
resultsOf 30,398 participants, 11,544 (37.98%) participants had CVD and 18,854 (62.02%) did not. Except for gender, the differences were significant between CVD and non-CVD participants in all variables (all
conclusionThere may be a synergistic interaction between depressive symptoms and sleep disorders, and the synergistic interaction may increase the occurrence of CVD.
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