ArticleInternational journal of general medicine2021
Origin of Sepsis Associated with the Short-Term Mortality of Patients: A Retrospective Study Using the eICU Collaborative Research Database.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 7 citations in OpenAlex.
- Personalized sepsis mortality prediction: An interpretable machine learning nomogram.Clinics (Sao Paulo, Brazil) · 2026Article
- Compartmental immunity in intra-abdominal infection: from peritoneal defense to systemic sepsis.Frontiers in immunology · 2026Review
- Sepsis Burden in a Major Romanian Emergency Center-An 18-Year Retrospective Analysis of Mortality and Risk Factors.Medicina (Kaunas, Lithuania) · 2025Article
- Targeting serum phosphate trajectory stratification to improve outcomes in high-risk Cardiovascular-Kidney-Metabolic-Sepsis cohorts.PloS one · 2025Article
- Association of serum phosphate and changes in serum phosphate with 28-day mortality in septic shock from MIMIC-IV database.Scientific reports · 2023Article
- Sepsis in a Combined Medical and Surgical High Dependency/Intensive Care Unit in Singapore: A Cohort Study and Survival Analysis.International journal of general medicine · 2022Article
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Authors and funding
9 authors at 1 institution in 1 country.
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Abstract
objectiveThe aim of this study was to compare the clinical characteristics and short-term mortality of patients with abdominal and pulmonary sepsis.
designRetrospective cohort study.
settingAdult intensive care units (ICUs) at tertiary hospitals.
participantsAdult ICU patients from 2014 to 2015 in the eICU Collaborative Research Database.
interventionsIn univariate analysis, we compared the differences in the characteristics of patients in each group. Logistic regression models were used to evaluate the relationships between primary site of sepsis and short-term prognosis. PRIMARY AND SECONDARY OUTCOME MEASURES: Hospital and ICU survival.
resultsThe final dataset included 7023 pulmonary and 2360 abdominal sepsis patients, who accounted for 74.84% and 25.16%, respectively. We compared the results of the baseline characteristics, vital signs and laboratory indicators between the two groups. In the logistic regression models, we found that the hospital and ICU mortality of patients with abdominal sepsis was higher than that with pulmonary sepsis (p < 0.05, OR = 1.15, p < 0.05, OR = 1.19, respectively), although these results were no longer significantly after adjustment for confounders, but in the subgroups with SOFA score ≧ 8, the adjusted hospital mortality rate of patients with abdominal sepsis was 1.30 times higher than that of patients with pulmonary sepsis (p < 0.005, OR = 1.30, 95% CI 1.09-1.55), while there was no significant difference in the subgroups that SOFA score < 8.
conclusionIn the patients with SOFA score ≧ 8, the adjusted hospital mortality of patients with abdominal sepsis was higher than patients with pulmonary sepsis.
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