ArticleJournal of inflammation research2021
Composite Inflammatory Indicators as Early Predictor of Intra-abdominal Infections after General Surgery.
Article in Journal of inflammation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Integrated fabrication of a shape-adaptable, antioxidative composite stent for effective closure and biological repair of enteroatmospheric fistula.Bioactive materials · 2026Article
- Diagnostic Value of Heparin-Binding Protein (HBP) in Pulmonary Infection After Radical Surgery for Lung Cancer: A Retrospective Study.Health science reports · 2026Article
- Value of Early Kinetics of Procalcitonin with Point-of-Care Test to Predict Postoperative Abscess Following Non-Complicated Acute Appendicitis: A Pilot Study.Medicina (Kaunas, Lithuania) · 2025Article
- Integrating serological and drainage fluid indicators: developing two predictive models for early detection of postoperative intra-abdominal infections in gastrointestinal tumor patients.Frontiers in oncology · 2025Article
- Interleukin-6 on postoperative day three as an early predictor of infections following laparoscopic gastric cancer resection.BMC surgery · 2024Article
- Development a risk prediction nomogram for multidrug-resistant bacterial and fungal infection in gastrointestinal fistula patients during the perioperative period.Frontiers in cellular and infection microbiology · 2024Article
- A Focus on Intra-Abdominal Sepsis with Biomarkers: A Literature Review.The Eurasian journal of medicine · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify rapid and accurate early diagnostic indicators for intra-abdominal infection (IAI) after general surgery.
methodsWe conducted a retrospective analysis of 3,810 general surgical patients in our hospital from August 2017 to July 2018. The predictive value of PCT, CRP, TNFα, and IL6 on postoperative days (PODs) 1 and 3 and composite indicators for complicated IAIs among surgical patients was clarified.
resultsThere were 271 patients in the infected group and 614 patients in the uninfected group using IAI diagnostic criteria in this study. CRP, PCT, TNFα, and IL6 in the infected group were significantly higher than the uninfected group on POD1 and POD3. In the infected group, the composition of the four indicators on POD1 (AUC 0.819) and POD3 (AUC 0.848) showed higher predictive efficiency than the individual indicators (AUC 0.670-0.805).
conclusionThe composite of CRP, PCT, TNFα, and IL6 can be used as a predictor of postoperative abdominal infectious complications with high sensitivity and specificity on POD1 and POD3, which can provide a basis for early diagnosis of postoperative abdominal infectious complications.
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