Evidence map›Paper›PMID 34992318›Full record

ArticleThe journal of extra-corporeal technology2021

To RAP or Not to RAP: A Retrospective Comparison of the Effects of Retrograde Autologous Priming.

Emily Foreman, Morgan Eddy, Jenny Holdcombe, Phoebe Warren, Lisa Gebicke, Pamela Raney, Wilson Clements, James Zellner

Open access · greenAbstract read
In one paragraph

Article in The journal of extra-corporeal technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emily ForemanCHI Memorial Hospital, Chattanooga, Tennessee.
Morgan EddyCHI Memorial Hospital, Chattanooga, Tennessee.
Jenny HoldcombeCHI Memorial Hospital, Chattanooga, Tennessee.
Phoebe WarrenCHI Memorial Hospital, Chattanooga, Tennessee.
Lisa GebickeCHI Memorial Hospital, Chattanooga, Tennessee.
Pamela RaneyCHI Memorial Hospital, Chattanooga, Tennessee.
Wilson ClementsCHI Memorial Hospital, Chattanooga, Tennessee.
James ZellnerCHI Memorial Hospital, Chattanooga, Tennessee.
CHI Memorial Medical Group · USMemorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrograde autologous priming (RAP) is a process used to reduce hemodilution associated with the initiation of cardiopulmonary bypass (CPB). Previous studies have reported potential benefits to RAP; however, many of these studies do not evaluate the benefits of RAP with limited preoperative fluid administration combined with a condensed CPB circuit. We examined clinical metrics of patients who underwent RAP versus those who did not undergo RAP prior to the initiation of CPB. This was a retrospective data review of 1,303 patients who underwent CPB in the setting of open-heart surgery for a 2-year period. RAP was used on all patients between June 1, 2017 and June 30, 2018 (

Indexed as

Blood Transfusion, AutologousCardiac Surgical ProceduresCardiopulmonary BypassHemodilutionHumansRetrospective Studiesacute kidney injury (AKI)cardiopulmonary bypass (CPB)oxygen delivery (DO2).retrograde autologous priming (RAP)

Identifiers

PMID34992318
PMCPMC8717721
OpenAlexW4205983337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.